دورية أكاديمية
Chemical and biological characteristics of propolis from Apis mellifera caucasica from the Ardahan and Erzurum provinces of Turkey: a comparative study
| العنوان: | Chemical and biological characteristics of propolis from Apis mellifera caucasica from the Ardahan and Erzurum provinces of Turkey: a comparative study |
|---|---|
| المؤلفون: | Arslan Mehmet, Sevgiler Yusuf, Güven Celal, Murathan Zehra Tuğba, Erbil Nurcan, Yıldırım Deniz, Büyükleyla Mehmet, Karadaş Şakire, Çelik Rima, Rencüzoğulları Eyyüp |
| المصدر: | Arhiv za Higijenu Rada i Toksikologiju, Vol 72, Iss 1, Pp 53-69 (2021) |
| بيانات النشر: | Sciendo, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Toxicology. Poisons |
| مصطلحات موضوعية: | anticarcinogen, antimicrobial, biological activity, mineral, mitomycin c, organic composition, antikancerogeno djelovanje, antimikrobno djelovanje, biološka aktivnost, minerali, mitomicin c, organski sastav, Toxicology. Poisons, RA1190-1270 |
| الوصف: | The aim of this study was to compare the biological activities of ethanolic propolis extracts of Apis mellifera caucasica obtained from Ardahan and Erzurum provinces of Turkey. Samples were tested for antioxidant, anticytotoxic, anticarcinogenic, antibacterial, and antifungal potentials using different techniques. Propolis samples from the two provinces had different mineral and organic compositions related to their geographical origin. The ferric reducing antioxidant power (FRAP) test showed superiority of Ardahan propolis over the Erzurum. Regardless of origin and the presence of mitomycin C in the culture medium, propolis enhanced human peripheral lymphocyte viability, which depended on the duration and propolis concentration. Antiperoxidative activity on MCF-7 breast cancer cells was concentration-dependent. Erzurum propolis showed the highest anticarcinogenic activity at the concentrations of 62.5 μg/mL and 125 μg/ mL, which dropped at higher concentrations. All propolis samples also showed antibacterial activity against the tested human pathogens similar to ampicillin and penicillin controls, except for Pseudomonas aeruginosa. However, they did not exert any antifungal activity against Candida albicans and Yarrowia lipolytica. In conclusion, propolis samples from both provinces showed promising biological activities, but further research should focus on finding the right concentrations for optimal effect and include the cell necrosis pathway to get a better idea of the anticarcinogenic effects. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Croatian |
| تدمد: | 1848-6312 |
| Relation: | https://doaj.org/toc/1848-6312 |
| DOI: | 10.2478/aiht-2021-72-3492 |
| URL الوصول: | https://doaj.org/article/9891d3c0937e4c569ea978e9a7e9a764 |
| رقم الأكسشن: | edsdoj.9891d3c0937e4c569ea978e9a7e9a764 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18486312 |
|---|---|
| DOI: | 10.2478/aiht-2021-72-3492 |