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Analysis of vaginal and endometrial microbiota communities in infertile women with a history of repeated implantation failure

التفاصيل البيبلوغرافية
العنوان: Analysis of vaginal and endometrial microbiota communities in infertile women with a history of repeated implantation failure
المؤلفون: Takuhiko Ichiyama, Keiji Kuroda, Yoko Nagai, Daichi Urushiyama, Motoharu Ohno, Takashi Yamaguchi, Motoi Nagayoshi, Yoshiyuki Sakuraba, Fumio Yamasaki, Kenichiro Hata, Shingo Miyamoto, Atsuo Itakura, Satoru Takeda, Atsushi Tanaka
المصدر: Reproductive Medicine and Biology, Vol 20, Iss 3, Pp 334-344 (2021)
بيانات النشر: Wiley, 2021.
سنة النشر: 2021
المجموعة: LCC:Diseases of the endocrine glands. Clinical endocrinology
LCC:Reproduction
مصطلحات موضوعية: 16S rRNA, bacterial vaginosis, dysbiosis, microbiome, microbiota, repeated implantation failure, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Reproduction, QH471-489
الوصف: Abstract Purpose To identify specific bacterial communities in vaginal and endometrial microbiotas as biomarkers of implantation failure by comprehensively analyzing their microbiotas using next‐generation sequencing. Methods We investigated α‐ and β‐diversities of vaginal and endometrial microbiotas using 16S rRNA gene sequencing and compared their profiles between 145 women with repeated implantation failure (RIF) and 21 controls who lacked the factors responsible for implantation failure with a high probability of being healthy and fertile to identify specific bacteria that induce implantation failure. Results The endometrial microbiotas had higher α‐diversities than did the vaginal microbiotas (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1447-0578
1445-5781
Relation: https://doaj.org/toc/1445-5781; https://doaj.org/toc/1447-0578
DOI: 10.1002/rmb2.12389
URL الوصول: https://doaj.org/article/d98b7730016c45308df890ca63baa2e6
رقم الأكسشن: edsdoj.98b7730016c45308df890ca63baa2e6
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14470578
14455781
DOI:10.1002/rmb2.12389