دورية أكاديمية
أعرض في EDS

HIV Infection and Acute Stroke: A Case Report and a Review of the Literature

التفاصيل البيبلوغرافية
العنوان: HIV Infection and Acute Stroke: A Case Report and a Review of the Literature
المؤلفون: Hussein Assallum, Mohammad Alkayem, Nehad Shabarek
المصدر: Case Reports in Medicine, Vol 2013 (2013)
بيانات النشر: Hindawi Limited, 2013.
سنة النشر: 2013
المجموعة: LCC:Medicine
مصطلحات موضوعية: Medicine
الوصف: Background. In the United States, ischemic stroke in HIV-infected patients has increased by 60%. However, unexpected cardiovascular events in relatively young patients have been observed. Clinical Vignette. A 31-year-old male who presented with a 5-hour history of sudden onset slurred speech and left hemiplegia. He has medical history of HIV infection for 2 years taking ARTs. On exam, a significant left hemiparesis was noticed. Brain MRI showed right anterior corona radiata and basal ganglia acute infarction. Discussion. Several mechanisms have been proposed for the relationship between HIV infection and cardiovascular risk. (i) HIV-associated dyslipidemia: HIV-infected patients tend to develop decrease in HDL-c and LDL-c levels. ART was associated with an increase in LDL-c but little change in HDL-c. (ii) Endothelial dysfunction: certain antiretroviral agents may independently contribute to endothelial damage. (iii) Hypertension: systolic blood pressure is higher in those using ART for greater than five years. (iv) Insulin resistance and diabetes have been noticed with ART. (v) Chronic inflammation. (vi) Hypercoagulability: decrease in proteins C and S was associated with HIV infection. Conclusion. Poorly controlled HIV infection and/or the introduction of ATR might be risk factors for cardiovascular events. More studies needed to address this medical dilemma.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1687-9627
1687-9635
Relation: https://doaj.org/toc/1687-9627; https://doaj.org/toc/1687-9635
DOI: 10.1155/2013/892054
URL الوصول: https://doaj.org/article/98da58c3e9a74bcab1ca570ec5847878
رقم الأكسشن: edsdoj.98da58c3e9a74bcab1ca570ec5847878
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16879627
16879635
DOI:10.1155/2013/892054