دورية أكاديمية
A Review of Nano/Micro/Milli Needles Fabrications for Biomedical Engineering
| العنوان: | A Review of Nano/Micro/Milli Needles Fabrications for Biomedical Engineering |
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| المؤلفون: | Bin Liu, Xin Yi, Ying Zheng, Zhishan Yuan, Jingbo Yang, Jian Yang, Xiao Yu, Lelun Jiang, Chengyong Wang |
| المصدر: | Chinese Journal of Mechanical Engineering, Vol 35, Iss 1, Pp 1-29 (2022) |
| بيانات النشر: | SpringerOpen, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Ocean engineering LCC:Mechanical engineering and machinery |
| مصطلحات موضوعية: | Nanoneedles, Microneedles, Millineedles, Fabrication methods, Biomedical Engineering, Ocean engineering, TC1501-1800, Mechanical engineering and machinery, TJ1-1570 |
| الوصف: | Abstract Needles, as some of the most widely used medical devices, have been effectively applied in human disease prevention, diagnosis, treatment, and rehabilitation. Thin 1D needle can easily penetrate cells/organs by generating highly localized stress with their sharp tips to achieve bioliquid sampling, biosensing, drug delivery, surgery, and other such applications. In this review, we provide an overview of multiscale needle fabrication techniques and their biomedical applications. Needles are classified as nanoneedles, microneedles and millineedles based on the needle diameter, and their fabrication techniques are highlighted. Nanoneedles bridge the inside and outside of cells, achieving intracellular electrical recording, biochemical sensing, and drug delivery. Microneedles penetrate the stratum corneum layer to detect biomarkers/bioelectricity in interstitial fluid and deliver drugs through the skin into the human circulatory system. Millineedles, including puncture, syringe, acupuncture and suture needles, are presented. Finally, conclusions and future perspectives for next-generation nano/micro/milli needles are discussed. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1000-9345 2192-8258 |
| Relation: | https://doaj.org/toc/1000-9345; https://doaj.org/toc/2192-8258 |
| DOI: | 10.1186/s10033-022-00773-6 |
| URL الوصول: | https://doaj.org/article/999caf2b0afb4d5f8f6b47e41fdaf697 |
| رقم الأكسشن: | edsdoj.999caf2b0afb4d5f8f6b47e41fdaf697 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 10009345 21928258 |
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| DOI: | 10.1186/s10033-022-00773-6 |