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Occupational Exposure to Diesel Motor Exhaust and Lung Cancer: A Dose-Response Relationship Hidden by Asbestos Exposure Adjustment? The ICARE Study

التفاصيل البيبلوغرافية
العنوان: Occupational Exposure to Diesel Motor Exhaust and Lung Cancer: A Dose-Response Relationship Hidden by Asbestos Exposure Adjustment? The ICARE Study
المؤلفون: Mireille Matrat, Florence Guida, Sylvie Cénée, Joelle Févotte, Matthieu Carton, Diane Cyr, Gwenn Menvielle, Sophie Paget-Bailly, Loredana Radoï, Annie Schmaus, Simona Bara, Michel Velten, Danièle Luce, Isabelle Stücker, The Icare Study Group
المصدر: Journal of Cancer Epidemiology, Vol 2015 (2015)
بيانات النشر: Hindawi Limited, 2015.
سنة النشر: 2015
المجموعة: LCC:Medicine
مصطلحات موضوعية: Medicine
الوصف: Background. In a French large population-based case-control study we investigated the dose-response relationship between lung cancer and occupational exposure to diesel motor exhaust (DME), taking into account asbestos exposure. Methods. Exposure to DME was assessed by questionnaire. Asbestos was taken into account through a global indicator of exposure to occupational carcinogens or by a specific JEM. Results. We found a crude dose response relationship with most of the indicators of DME exposure, including with the cumulative exposure index. All results were affected by adjustment for asbestos exposure. The dose response relationships between DME and lung cancer were observed among subjects never exposed to asbestos. Conclusions. Exposure to DME and to asbestos is frequently found among the same subjects, which may explain why dose-response relationships in previous studies that adjusted for asbestos exposure were inconsistent.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1687-8558
1687-8566
Relation: https://doaj.org/toc/1687-8558; https://doaj.org/toc/1687-8566
DOI: 10.1155/2015/879302
URL الوصول: https://doaj.org/article/a9aa8404cc2341ab94c156bb455d9ff4
رقم الأكسشن: edsdoj.9aa8404cc2341ab94c156bb455d9ff4
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16878558
16878566
DOI:10.1155/2015/879302