دورية أكاديمية
Intravoxel Incoherent Motion (IVIM) Diffusion-Weighted Imaging (DWI) in Patients with Liver Dysfunction of Chronic Viral Hepatitis: Segmental Heterogeneity and Relationship with Child-Turcotte-Pugh Class at 3 Tesla
| العنوان: | Intravoxel Incoherent Motion (IVIM) Diffusion-Weighted Imaging (DWI) in Patients with Liver Dysfunction of Chronic Viral Hepatitis: Segmental Heterogeneity and Relationship with Child-Turcotte-Pugh Class at 3 Tesla |
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| المؤلفون: | Lei Ding, Lianxiang Xiao, Xiangtao Lin, Chunmei Xiong, Lingbo Lin, Shijun Chen |
| المصدر: | Gastroenterology Research and Practice, Vol 2018 (2018) |
| بيانات النشر: | Wiley, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Background. Few studies focused on the region of interest- (ROI-) related heterogeneity of liver intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI). The aim of the study was to evaluate the differences of liver IVIM parameters among liver segments in cirrhotic livers (chronic viral hepatitis). Material and Methods. This was a retrospective study of 82 consecutive patients with chronic liver disease who underwent MRI examination at the Jinan Infectious Diseases Hospital between January 2015 and December 2016. IVIM DWI (seven different b values) was performed on a Siemens 3.0-T MRI scanner. Pure molecular diffusion (D), pseudodiffusion (D∗), and perfusion fraction (f) in different liver segments were evaluated. Results. f, D, and D∗ were different among the liver segments (all p0.29, the AUC was 0.88 (95% CI: 0.81-0.96), with 86.8% sensitivity and 81.8% specificity for predicting CTP class A from CTP class B + C. Conclusion. Liver IVIM could be a promising method for classifying the severity of segmental liver dysfunction of chronic viral hepatitis as evaluated by the CTP class, which provides a noninvasive alternative for evaluating segmental liver dysfunction with accurate selection of ROIs. Potentially it can be used to monitor the progression of CLD and LC in the future. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1687-6121 1687-630X |
| Relation: | https://doaj.org/toc/1687-6121; https://doaj.org/toc/1687-630X |
| DOI: | 10.1155/2018/2983725 |
| URL الوصول: | https://doaj.org/article/9b96d74240e3420e938b417a0abc67d8 |
| رقم الأكسشن: | edsdoj.9b96d74240e3420e938b417a0abc67d8 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16876121 1687630X |
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| DOI: | 10.1155/2018/2983725 |