دورية أكاديمية
Functional connectome differences in individuals with hallucinations across the psychosis continuum
| العنوان: | Functional connectome differences in individuals with hallucinations across the psychosis continuum |
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| المؤلفون: | Maya J. L. Schutte, Marc M. Bohlken, Guusje Collin, Lucija Abramovic, Marco P. M. Boks, Wiepke Cahn, Meenakshi Dauwan, Edwin van Dellen, Neeltje E. M. van Haren, Kenneth Hugdahl, Sanne Koops, René C. W. Mandl, Iris E. C. Sommer |
| المصدر: | Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021) |
| بيانات النشر: | Nature Portfolio, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | Abstract Hallucinations may arise from an imbalance between sensory and higher cognitive brain regions, reflected by alterations in functional connectivity. It is unknown whether hallucinations across the psychosis continuum exhibit similar alterations in functional connectivity, suggesting a common neural mechanism, or whether different mechanisms link to hallucinations across phenotypes. We acquired resting-state functional MRI scans of 483 participants, including 40 non-clinical individuals with hallucinations, 99 schizophrenia patients with hallucinations, 74 bipolar-I disorder patients with hallucinations, 42 bipolar-I disorder patients without hallucinations, and 228 healthy controls. The weighted connectivity matrices were compared using network-based statistics. Non-clinical individuals with hallucinations and schizophrenia patients with hallucinations exhibited increased connectivity, mainly among fronto-temporal and fronto-insula/cingulate areas compared to controls (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-020-80657-8 |
| URL الوصول: | https://doaj.org/article/9bc923f74f784c3fa696160b7e4da7e1 |
| رقم الأكسشن: | edsdoj.9bc923f74f784c3fa696160b7e4da7e1 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20452322 |
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| DOI: | 10.1038/s41598-020-80657-8 |