دورية أكاديمية
Astaxanthin and improvement of dementia: A systematic review of current clinical trials
| العنوان: | Astaxanthin and improvement of dementia: A systematic review of current clinical trials |
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| المؤلفون: | Nunki Puspita Utomo, Rizaldy Taslim Pinzon, Patrick Kurniawan Latumahina, Kadex Reisya Sita Damayanti |
| المصدر: | Cerebral Circulation - Cognition and Behavior, Vol 7, Iss , Pp 100226- (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Specialties of internal medicine LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
| مصطلحات موضوعية: | Astaxanthin, Cognitive impairment, Dementia, Geriatric, Specialties of internal medicine, RC581-951, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| الوصف: | Worldwide, the incidence of neurodegenerative diseases especially dementia is steadily increasing due to the aging population. Abundant research emerges on the probability of combating or preventing the degeneration process, with the most established one being to tackle the existence of oxidative stress and free radicals production due to their nature of aggravating dementia. Astaxanthin, a marine carotenoid, was proven to be a protective agent of cerebral ischemia through many animal model clinical trials. This review summarizes the evidence of Astaxanthin's benefits for cognitive function across clinical trials done in older age. The results are of interest as its supplementation does not exhibit unwanted issues on the consumer based on physical and laboratory examinations. Despite not being supported statistically, however, subjective and objective cognitive amelioration were reported according to the majority of this review's trial subjects. Although there is no clear and direct mechanism for cognitive improvement by Astaxanthin activity in the body systems, the encouragement of Astaxanthin supplementation should be considered as the elderly with dementia may highly benefit from the improved cognitive function. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2666-2450 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2666245024000278; https://doaj.org/toc/2666-2450 |
| DOI: | 10.1016/j.cccb.2024.100226 |
| URL الوصول: | https://doaj.org/article/d9cc5c9293aa4a7199e15bb37547cde0 |
| رقم الأكسشن: | edsdoj.9cc5c9293aa4a7199e15bb37547cde0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 26662450 |
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| DOI: | 10.1016/j.cccb.2024.100226 |