دورية أكاديمية
Chronic Calcifying Pancreatitis Associated with Secondary Diabetes Mellitus and Hepatosplenic Abscesses in a Young Male Patient: A Case Report
| العنوان: | Chronic Calcifying Pancreatitis Associated with Secondary Diabetes Mellitus and Hepatosplenic Abscesses in a Young Male Patient: A Case Report |
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| المؤلفون: | Cristina Maria Marginean, Mihaela Popescu, Corina Maria Vasile, Mihaela Stanciu, Iulian Alin Popescu, Viorel Biciusca, Daniela Ciobanu, Amelia Dobrescu, Larisa Daniela Sandulescu, Simona Bondari, Marian Sorin Popescu, Paul Mitrut |
| المصدر: | Gastroenterology Insights, Vol 13, Iss 3, Pp 305-312 (2022) |
| بيانات النشر: | MDPI AG, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | chronic calcifying pancreatitis, computed tomography, hepatosplenic abscesses, diabetes mellitus, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Background: Chronic pancreatitis (CP) has been described as a multifactorial, ongoing inflammatory condition of the pancreas of varying intensity that produces persistent pain, leading to exocrine and endocrine insufficiency and a decreased lifespan. Currently, there are three primary forms of chronic pancreatitis: chronic autoimmune pancreatitis (steroid-sensitive pancreatitis), chronic obstructive pancreatitis, and chronic calcific pancreatitis, the latter being closely related to excessive alcohol consumption for one or even two decades before the onset of symptoms. Case report: We present the case of a 29 year old man who required medical attention for a significant unintentional weight loss and a history of upper abdominal pain. Blood tests revealed substantial abnormalities, and the patient was admitted for further investigation. CT and MRI confirmed the presence of a pancreatic pseudocyst and extensive pancreatic parenchymal calcifications and revealed multiple hepatosplenic microabscesses of fungal etiology. Conclusions: Chronic calcifying pancreatitis is a complex clinical entity that can lead to secondary diabetes due to progressive destruction of the pancreatic parenchyma. Protein malnutrition, caused by malabsorption syndrome, immune cell dysfunction, and a high glucose environment caused by diabetes mellitus, may create a state of immunodeficiency, predisposing the patient to opportunistic infections. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2036-7422 2036-7414 |
| Relation: | https://www.mdpi.com/2036-7422/13/3/31; https://doaj.org/toc/2036-7414; https://doaj.org/toc/2036-7422 |
| DOI: | 10.3390/gastroent13030031 |
| URL الوصول: | https://doaj.org/article/ac9db6a3278d4c00b503937cf2614683 |
| رقم الأكسشن: | edsdoj.9db6a3278d4c00b503937cf2614683 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20367422 20367414 |
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| DOI: | 10.3390/gastroent13030031 |