دورية أكاديمية
Long-Term Outcomes of Adult Lung Transplantation Recipients: A Single-Center Experience in South Korea
| العنوان: | Long-Term Outcomes of Adult Lung Transplantation Recipients: A Single-Center Experience in South Korea |
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| المؤلفون: | Kyung-Wook Jo, M.D., Ph.D., Sang-Bum Hong, M.D., Ph.D., Dong Kwan Kim, M.D., Ph.D., Sung Ho Jung, M.D., Ph.D., Hyeong Ryul Kim, M.D., Ph.D., Se Hoon Choi, M.D., Ph.D., Geun Dong Lee, M.D., Ph.D., Sang-Oh Lee, M.D., Ph.D., Kyung-Hyun Do, M.D., Ph.D., Eun Jin Chae, M.D., Ph.D., In-Cheol Choi, M.D., Ph.D., Dae-Kee Choi, M.D., Ph.D., In Ok Kim, M.Sc., Seung-Il Park, M.D., Ph.D., Tae Sun Shim, M.D., Ph.D. |
| المصدر: | Tuberculosis and Respiratory Diseases, Vol 82, Iss 4, Pp 348-356 (2019) |
| بيانات النشر: | The Korean Academy of Tuberculosis and Respiratory Diseases, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Diseases of the respiratory system |
| مصطلحات موضوعية: | lung transplantation, survival, chronic lung allograft dysfunction, chronic kidney disease, Diseases of the respiratory system, RC705-779 |
| الوصف: | Background Recently, the number of lung transplants in South Korea has increased. However, the long-term outcome data is limited. In this study, we aimed to investigate the long-term outcomes of adult lung transplantation recipients. Methods Among the patients that underwent lung transplantation at a tertiary referral center in South Korea between 2008 and 2017, adults patient who underwent deceased-donor lung transplantation with available follow-up data were enrolled. Their medical records were retrospectively reviewed. Results Through eligibility screening, we identified 60 adult patients that underwent lung (n=51) or heart-lung transplantation (n=9) during the observation period. Idiopathic pulmonary fibrosis (46.7%, 28/60) was the most frequent cause of lung transplantation. For all the 60 patients, the median follow-up duration for post-transplantation was 2.6 years (range, 0.01–7.6). During the post-transplantation follow-up period, 19 patients (31.7%) died at a median duration of 194 days. The survival rates were 75.5%, 67.6%, and 61.8% at 1 year, 3 years, and 5 years, respectively. Out of the 60 patients, 8 (13.3%) were diagnosed with chronic lung allograft dysfunction (CLAD), after a mean duration of 3.3±2.8 years post-transplantation. The CLAD development rate was 0%, 17.7%, and 25.8% at 1 year, 3 years, and 5 years, respectively. The most common newly developed post-transplantation comorbidity was the chronic kidney disease (CKD; 54.0%), followed by diabetes mellitus (25.9%). Conclusion Among the adult lung transplantation recipients at a South Korea tertiary referral center, the long-term survival rates were favorable. The proportion of patients who developed CLAD was not substantial. CKD was the most common post-transplantation comorbidity. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1738-3536 2005-6184 |
| Relation: | https://www.e-trd.org/search.php?where=aview&id=10.4046/trd.2019.0016&code=0003TRD&vmode=FULL; https://doaj.org/toc/1738-3536; https://doaj.org/toc/2005-6184 |
| DOI: | 10.4046/trd.2019.0016&code=0003TRD&vmode=FULL |
| URL الوصول: | https://doaj.org/article/9e73c7284f1f4f1c802cb96fb71e5d33 |
| رقم الأكسشن: | edsdoj.9e73c7284f1f4f1c802cb96fb71e5d33 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17383536 20056184 |
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| DOI: | 10.4046/trd.2019.0016&code=0003TRD&vmode=FULL |