دورية أكاديمية
CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst
| العنوان: | CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst |
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| المؤلفون: | Sebastián Zagmutt, Paula Mera, Ismael González-García, Kevin Ibeas, María del Mar Romero, Arnaud Obri, Beatriz Martin, Anna Esteve-Codina, M. Carmen Soler-Vázquez, Marianela Bastias-Pérez, Laia Cañes, Elisabeth Augé, Carme Pelegri, Jordi Vilaplana, Xavier Ariza, Jordi García, José Martinez-González, Núria Casals, Miguel López, Richard Palmiter, Elisenda Sanz, Albert Quintana, Laura Herrero, Dolors Serra |
| المصدر: | Biology of Sex Differences, Vol 14, Iss 1, Pp 1-26 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Physiology |
| مصطلحات موضوعية: | CPT1A, Fatty acid metabolism, AgRP neurons, Energy balance, Food intake, Thirst, Medicine, Physiology, QP1-981 |
| الوصف: | Highlights Fatty acid metabolism and CPT1A in AgRP neurons show marked sex-dependent differences in the control of feeding. Cpt1a gene deletion in AgRP neurons increases energy expenditure in females but not in males. CPT1A in AgRP neurons is involved in the control of thirst and fluid homeostasis. Cpt1a gene deletion in AgRP neurons induces morphological, mitochondrial, and gene expression alterations in a sex-dependent manner. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2042-6410 |
| Relation: | https://doaj.org/toc/2042-6410 |
| DOI: | 10.1186/s13293-023-00498-8 |
| URL الوصول: | https://doaj.org/article/9eef829aeb3f49da853bf659361e7019 |
| رقم الأكسشن: | edsdoj.9eef829aeb3f49da853bf659361e7019 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20426410 |
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| DOI: | 10.1186/s13293-023-00498-8 |