دورية أكاديمية
Diagnostic accuracy of urine dipstick for proteinuria in older outpatients
| العنوان: | Diagnostic accuracy of urine dipstick for proteinuria in older outpatients |
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| المؤلفون: | Dongmin Lim, Dong-Young Lee, Soung Ha Cho, One Zoong Kim, Sang Woo Cho, Su Kyoung An, Hwe Won Kim, Kyoung Hyoub Moon, Myung Hee Lee, Beom Kim |
| المصدر: | Kidney Research and Clinical Practice, Vol 33, Iss 4, Pp 199-203 (2014) |
| بيانات النشر: | The Korean Society of Nephrology, 2014. |
| سنة النشر: | 2014 |
| المجموعة: | LCC:Internal medicine LCC:Specialties of internal medicine |
| مصطلحات موضوعية: | Albuminuria, Proteinuria, Reagent strips, ROC curve, Internal medicine, RC31-1245, Specialties of internal medicine, RC581-951 |
| الوصف: | Background: The urine dipstick is widely used as an initial screening tool for the evaluation of proteinuria; however, its diagnostic accuracy has not yet been sufficiently evaluated. Therefore, we evaluated its diagnostic accuracy using spot urine albumin/creatinine ratio (ACR) and total protein/creatinine ratio (PCR) in proteinuria. Methods: Using PCR ≥0.2 g/g or ≥0.5 g/g and ACR ≥300 mg/g or ≥30 mg/g as the reference standard, we calculated the diagnostic accuracy profile: sensitivity, specificity, positive and negative predictive value, and the area under the curve (AUC) of the receiver operating characteristic curve. Results: PCR and ACR were available for 10,348 and 3,873 instances of dipstick testing. The proportions with PCR ≥0.2 g/g, ≥0.5 g/g and ACR ≥300 mg/g, ≥30 mg/g were 38.2%, 24.6% and 8.9%, 31.7%, respectively. The AUCs for PCR ≥0.2 g/g, ≥0.5 g/g, and ACR ≥300 mg/g were 0.935 (trace: closest to ideal point), 0.968 (1+), and 0.983 (1+), respectively. Both sensitivity and specificity were >80% except for PCR ≥0.5 g/g with trace cutoff. For the reference standard of ACR ≥30 mg/g, the AUC was 0.797 (trace) and the sensitivity was 63.5%. Conclusion: Urine dipstick test can be used for screening in older outpatients with ACR ≥300 mg/g or PCR as the reference standard for proteinuria. However, we cannot recommend the test as a screening tool with ACR ≥30 mg/g as the reference owing to its low sensitivity. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Korean |
| تدمد: | 2211-9132 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2211913214001272; https://doaj.org/toc/2211-9132 |
| DOI: | 10.1016/j.krcp.2014.10.003 |
| URL الوصول: | https://doaj.org/article/b035e96f0941436e9049bbe6ce36d5b6 |
| رقم الأكسشن: | edsdoj.b035e96f0941436e9049bbe6ce36d5b6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22119132 |
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| DOI: | 10.1016/j.krcp.2014.10.003 |