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Immunoreactivities of PPARγ2, leptin and leptin receptor in oviduct of Chinese brown frog during breeding period and pre-hibernation

التفاصيل البيبلوغرافية
العنوان: Immunoreactivities of PPARγ2, leptin and leptin receptor in oviduct of Chinese brown frog during breeding period and pre-hibernation
المؤلفون: Y. Liu, J. Weng, S. Huang, Y. Shen, X. Sheng, Y. Han, M. Xu, Q. Weng
المصدر: European Journal of Histochemistry, Vol 58, Iss 3 (2014)
بيانات النشر: PAGEPress Publications, 2014.
سنة النشر: 2014
المجموعة: LCC:Biology (General)
مصطلحات موضوعية: Leptin, leptin receptor, oviduct, PPARγ2, Rana dybowskii., Biology (General), QH301-705.5
الوصف: The Chinese brown frog (Rana dybowskii) is a special amphibian with one unique physiological phenomenon, which is that its oviduct expands prior to hibernation, instead of during the breeding period. In this study, we investigate the localization and expression level of PPARγ2, leptin and leptin receptor proteins in oviduct of Rana dybowskii during breeding period and pre-hibernation. There were significant variations in oviductal weight and size, with values much lower in the breeding period than in pre-hibernation. PPARγ2 was observed in stromal and epithelial cells in both periods. Leptin was immunolocalized in epithelial cells in both periods, whereas leptin receptor was detected only in stromal cells. Consistently, the protein levels of PPARγ2, leptin and leptin receptor were higher in pre-hibernation as compared to the breeding period. These results suggested that oviduct was the target organ of leptin, which may play an important paracrine role in regulating the oviductal hypertrophy during pre-hibernation.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1121-760X
2038-8306
Relation: http://www.ejh.it/index.php/ejh/article/view/2422; https://doaj.org/toc/1121-760X; https://doaj.org/toc/2038-8306
DOI: 10.4081/ejh.2014.2422
URL الوصول: https://doaj.org/article/b101da42c6b94b8a86fcc6e36c98e035
رقم الأكسشن: edsdoj.b101da42c6b94b8a86fcc6e36c98e035
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1121760X
20388306
DOI:10.4081/ejh.2014.2422