دورية أكاديمية
Recent Advances in Zein-Based Nanocarriers for Precise Cancer Therapy
| العنوان: | Recent Advances in Zein-Based Nanocarriers for Precise Cancer Therapy |
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| المؤلفون: | Wenquan Huang, Fei Yao, Shuangyan Tian, Mohao Liu, Guijin Liu, Yanbin Jiang |
| المصدر: | Pharmaceutics, Vol 15, Iss 7, p 1820 (2023) |
| بيانات النشر: | MDPI AG, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Pharmacy and materia medica |
| مصطلحات موضوعية: | zein, nanocarrier, anticancer, precision medicine, Pharmacy and materia medica, RS1-441 |
| الوصف: | Cancer has emerged as a leading cause of death worldwide. However, the pursuit of precise cancer therapy and high-efficiency delivery of antitumor drugs remains an enormous obstacle. The major challenge is the lack of a smart drug delivery system with the advantages of biodegradability, biocompatibility, stability, targeting and response release. Zein, a plant-based protein, possesses a unique self-assembly ability to encapsulate anticancer drugs directly or indirectly. Using zein as a nanotherapeutic pharmaceutic preparation can protect anticancer drugs from harsh environments, such as sunlight, stomach acid and pepsin. Moreover, the surface functionalization of zein is easily realized, which can endow it with targeting and stimulus-responsive release capacity. Hence, zein is an ideal nanocarrier for the precise delivery of anticancer drugs. Combined with our previous research experiences, we attempt to review the current state of the preparation of zein-based nanocarriers for anticancer drug delivery. The challenges, solutions and development trends of zein-based nanocarriers for precise cancer therapy are discussed. This review will provide a guideline for precise cancer therapy in the future. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 15071820 1999-4923 |
| Relation: | https://www.mdpi.com/1999-4923/15/7/1820; https://doaj.org/toc/1999-4923 |
| DOI: | 10.3390/pharmaceutics15071820 |
| URL الوصول: | https://doaj.org/article/b1501b02010545408c6fad392b314631 |
| رقم الأكسشن: | edsdoj.b1501b02010545408c6fad392b314631 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15071820 19994923 |
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| DOI: | 10.3390/pharmaceutics15071820 |