دورية أكاديمية
Predictors for pharmacological therapy and perinatal outcomes with metformin treatment in women with gestational diabetes
| العنوان: | Predictors for pharmacological therapy and perinatal outcomes with metformin treatment in women with gestational diabetes |
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| المؤلفون: | Malgorzata M. Brzozowska, Anita Puvanendran, Dana Bliuc, Andrew Zuschmann, Agata K. Piotrowicz, Anthony O’Sullivan |
| المصدر: | Frontiers in Endocrinology, Vol 14 (2023) |
| بيانات النشر: | Frontiers Media S.A., 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: | gestational diabetes mellitus, dietary intervention, perinatal outcomes, metformin, treatment predictors, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: | BackgroundThe prevalence of gestational diabetes mellitus (GDM) has been increasing in Australia and worldwide. The study aims were to examine, in comparison with dietary intervention, perinatal outcomes for women with gestational diabetes who were attending a single hospital clinic and to identify predictors for their pharmacological GDM treatment.MethodsA prospective, observational study of women with GDM, treated with “Diet, N= 50”, “Metformin, N = 35”, “Metformin and Insulin, N = 46” or “Insulin, N = 20”.FindingsThe mean BMI for the whole cohort was 25.8 ± 4.7 kg/m2. The Metformin group, compared to the Diet group, had OR=3.1 (95% CI:1.13 to 8.25) for caesarean section birth (LSCS) compared to normal vaginal birth mode with no longer such a significant association after controlling for the number of their elective LSCS. The insulin treated group had the highest number of small for gestational age neonates (20%, p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1664-2392 74566911 |
| Relation: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1119134/full; https://doaj.org/toc/1664-2392 |
| DOI: | 10.3389/fendo.2023.1119134 |
| URL الوصول: | https://doaj.org/article/b196cae175c74566911b7f7a3a12d72f |
| رقم الأكسشن: | edsdoj.b196cae175c74566911b7f7a3a12d72f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16642392 74566911 |
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| DOI: | 10.3389/fendo.2023.1119134 |