دورية أكاديمية
أعرض في EDS

Venovenous extra-corporeal membrane oxygenation for severe acute respiratory distress syndrome: a matched cohort study

التفاصيل البيبلوغرافية
العنوان: Venovenous extra-corporeal membrane oxygenation for severe acute respiratory distress syndrome: a matched cohort study
المؤلفون: Song-Qiao Liu, Ying-Zi Huang, Chun Pan, Lan-Qi Guo, Xiao-Ting Wang, Wen-Kui Yu, Yun-Fu Wu, Jie Yan, Hong-Sheng Zhao, Ling Liu, Feng-Mei Guo, Jing-Yuan Xu, Yi Yang, Hai-Bo Qiu, Qiang Shi
المصدر: Chinese Medical Journal, Vol 132, Iss 18, Pp 2192-2198 (2019)
بيانات النشر: Wolters Kluwer, 2019.
سنة النشر: 2019
المجموعة: LCC:Medicine
مصطلحات موضوعية: Medicine
الوصف: Abstract. Background:. Although the use of extra-corporeal membrane oxygenation (ECMO) has been rapidly increasing, the benefit of ECMO in patients with acute respiratory distress syndrome (ARDS) remains unclear. Our objective was to investigate the effect of venovenous ECMO (VV-ECMO) on adult patients with severe ARDS. Methods:. We conducted a multi-center, retrospective, cohort study in the intensive care units (ICUs) of six teaching hospitals between January 2013 and December 2018. Patients with severe ARDS who received VV-ECMO support were included. The detailed demographic data and physiologic data were used to match ARDS patients without ECMO. The primary endpoint was the 28-day mortality. Results:. Ninety-nine patients with severe ARDS supported by VV-ECMO and 72 patients without ECMO were included in this study. The acute physiology and chronic health evaluation II score was 23.1 ± 6.3 in the ECMO group and 24.8 ± 8.5 in the control group (P = 0.1195). The sequential organ failure assessment score was 12.8 ± 3.4 in the ECMO group and 13.7 ± 3.5 in the control group (P = 0.0848). The 28-day mortality of patients with ECMO support was 39.4%, and that of the control group was 55.6%. The survival analysis curve showed that the 28-day mortality in the ECMO group was significantly lower than that in the control group (P = 0.0097). Multivariate Cox regression analysis showed that the independent predictors of the 28-day mortality were the requirement of vasopressors before ECMO (hazard ratio [HR]: 1.006; 95% confidence interval [CI]: 1.001–1.013; P = 0.030) and duration of mechanical ventilation before ECMO (HR: 3.299; 95% CI: 1.264–8.609; P = 0.034). Conclusions:. This study showed that ECMO improved the survival of patients with severe ARDS. The duration of mechanical ventilation and the requirement of vasopressors before ECMO might be associated with an increased risk of death.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0366-6999
2542-5641
00000000
Relation: http://journals.lww.com/10.1097/CM9.0000000000000424; https://doaj.org/toc/0366-6999; https://doaj.org/toc/2542-5641
DOI: 10.1097/CM9.0000000000000424
URL الوصول: https://doaj.org/article/b1a94550df22495380662ce2a6649f6c
رقم الأكسشن: edsdoj.b1a94550df22495380662ce2a6649f6c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:03666999
25425641
00000000
DOI:10.1097/CM9.0000000000000424