دورية أكاديمية
Synthesis of 2-oxindoles via 'transition-metal-free' intramolecular dehydrogenative coupling (IDC) of sp2 C–H and sp3 C–H bonds
| العنوان: | Synthesis of 2-oxindoles via 'transition-metal-free' intramolecular dehydrogenative coupling (IDC) of sp2 C–H and sp3 C–H bonds |
|---|---|
| المؤلفون: | Nivesh Kumar, Santanu Ghosh, Subhajit Bhunia, Alakesh Bisai |
| المصدر: | Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1153-1169 (2016) |
| بيانات النشر: | Beilstein-Institut, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Science LCC:Organic chemistry |
| مصطلحات موضوعية: | C−H functionalization, intramolecular dehydrogenative coupling (IDC), iodine, N-iodosuccinimide, oxidants, 2-oxindoles, Science, Organic chemistry, QD241-441 |
| الوصف: | The synthesis of a variety of 2-oxindoles bearing an all-carbon quaternary center at the pseudo benzylic position has been achieved via a ‘transition-metal-free’ intramolecular dehydrogenative coupling (IDC). The construction of 2-oxindole moieties was carried out through formation of carbon–carbon bonds using KOt-Bu-catalyzed one pot C-alkylation of β-N-arylamido esters with alkyl halides followed by a dehydrogenative coupling. Experimental evidences indicated toward a radical-mediated path for this reaction. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1860-5397 |
| Relation: | https://doaj.org/toc/1860-5397 |
| DOI: | 10.3762/bjoc.12.111 |
| URL الوصول: | https://doaj.org/article/eb1da2952bb4400fba8467ca81926af0 |
| رقم الأكسشن: | edsdoj.b1da2952bb4400fba8467ca81926af0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18605397 |
|---|---|
| DOI: | 10.3762/bjoc.12.111 |