دورية أكاديمية

5-year oncological outcomes in left-sided malignant colonic obstruction: stent as bridge to surgery

التفاصيل البيبلوغرافية
العنوان: 5-year oncological outcomes in left-sided malignant colonic obstruction: stent as bridge to surgery
المؤلفون: Noura S Alhassan, Sulaiman A AlShammari, Razan N AlRabah, Amirah M AlZahrani, Maha-Hamadien Abdulla, Thamer A Bin Traiki, Ahmad M Zubaidi, Omar A Al-Obeed, Khayal A Alkhayal
المصدر: BMC Gastroenterology, Vol 23, Iss 1, Pp 1-8 (2023)
بيانات النشر: BMC, 2023.
سنة النشر: 2023
المجموعة: LCC:Diseases of the digestive system. Gastroenterology
مصطلحات موضوعية: SEMS, Oncological outcomes, Malignant colonic obstruction, Upfront surgery, Diseases of the digestive system. Gastroenterology, RC799-869
الوصف: Abstract Background A considerable number of patients with colon cancer present with a colonic obstruction. The use of self-expanding metallic stents (SEMS) as a bridge to surgery (BTS) in potential curative patients with left-sided colonic cancer obstruction remains debatable. Therefore, this study aimed to investigate the 5-year oncological outcomes of using a SEMS as a BTS. Methods All patients with left-sided malignant colon obstruction who underwent curative surgery with no metastasis upon presentation between March 2009 and May 2013 were retrospectively reviewed and analyzed. Results A total of 45 patients were included, 28 patients underwent upfront surgery, and 17 patients had a stent as a bridge to surgery. T4 stage was statistically significantly higher in patients who had a SEMS as a BTS (35.3% vs. 10.7%) (p-value 0.043). The mean duration in days of the SEMS to surgery was 13.76 (SD 10.08). TNM stage 3 was a prognostic factor toward distant metastasis (HR 5.05). When comparing patients who had upfront surgery to those who had a SEMS as a BTS, higher 5-year disease-free survival (75% vs. 72%) and 5-year overall survival (89% vs. 82%) were seen in patients who had upfront surgery. However, both were statistically insignificant. Conclusion Using self-expanding metallic stents as a bridge to surgery yields comparable 5-year survival and disease-free survival rates to upfront emergency surgery. The decision to use SEMS versus opting for emergency surgery should be made after careful patient selection and with the assistance of experienced endoscopists. Trial registration N/A.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-230X
Relation: https://doaj.org/toc/1471-230X
DOI: 10.1186/s12876-023-02903-3
URL الوصول: https://doaj.org/article/b1eed17d695a414c8dd572256c3127ac
رقم الأكسشن: edsdoj.b1eed17d695a414c8dd572256c3127ac
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1471230X
DOI:10.1186/s12876-023-02903-3