دورية أكاديمية
Relationship between Antithrombin III Activity and Mortality in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
| العنوان: | Relationship between Antithrombin III Activity and Mortality in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease |
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| المؤلفون: | Shuling Zhang, Xiaoguang Li, Haili Ma, Mengpei Zhu, Yuequan Zhou, Qianqian Zhang, Hongxing Peng |
| المصدر: | COPD, Vol 19, Iss 1, Pp 353-364 (2022) |
| بيانات النشر: | Taylor & Francis Group, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the respiratory system |
| مصطلحات موضوعية: | copd, antithrombin iii, thrombin, mortality, Diseases of the respiratory system, RC705-779 |
| الوصف: | We aimed to explore the role of antithrombin III (AT-III) activity in diagnosing patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and chronic bronchitis, and its relationship with all-cause mortality of AECOPD patients. We performed univariate and multivariate Cox regression analyses of the factors determining all-cause mortality. We recruited 279 patients with AECOPD and 91 with chronic bronchitis. On admission, patients with AECOPD had lower AT-III activity (80.7 vs. 86.35%, p = 0.002) and higher neutrophil percentages (70.12 vs. 66.40%, p = 0.02) than those with chronic bronchitis. The patients who died were older (78 vs. 73 years, p 79.75%. AT-III activity was lower in patients with AECOPD than in those with chronic bronchitis and is potentially useful as an independent predictor of all-cause mortality in patients with AECOPD: reduced AT-III activity and increased CRP and D-dimer levels indicate a higher risk of all-cause mortality. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1541-2555 1541-2563 15412555 |
| Relation: | https://doaj.org/toc/1541-2555; https://doaj.org/toc/1541-2563 |
| DOI: | 10.1080/15412555.2022.2106200 |
| URL الوصول: | https://doaj.org/article/b2c4d3504bb64610ac90ed5475db796c |
| رقم الأكسشن: | edsdoj.b2c4d3504bb64610ac90ed5475db796c |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 15412555 15412563 |
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| DOI: | 10.1080/15412555.2022.2106200 |