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Review: Animal model and the current understanding of molecule dynamics of adipogenesis

التفاصيل البيبلوغرافية
العنوان: Review: Animal model and the current understanding of molecule dynamics of adipogenesis
المؤلفون: C.F. Campos, M.S. Duarte, S.E.F. Guimarães, L.L. Verardo, S. Wei, M. Du, Z. Jiang, W.G. Bergen, G.J. Hausman, M. Fernyhough-Culver, E. Albrecht, M.V. Dodson
المصدر: Animal, Vol 10, Iss 6, Pp 927-932 (2016)
بيانات النشر: Elsevier, 2016.
سنة النشر: 2016
المجموعة: LCC:Animal culture
مصطلحات موضوعية: wagyu, adipogenesis, lipodystrophies, obesity, Animal culture, SF1-1100
الوصف: Among several potential animal models that can be used for adipogenic studies, Wagyu cattle is the one that presents unique molecular mechanisms underlying the deposit of substantial amounts of intramuscular fat. As such, this review is focused on current knowledge of such mechanisms related to adipose tissue deposition using Wagyu cattle as model. So abundant is the lipid accumulation in the skeletal muscles of these animals that in many cases, the muscle cross-sectional area appears more white (adipose tissue) than red (muscle fibers). This enhanced marbling accumulation is morphologically similar to that seen in numerous skeletal muscle dysfunctions, disease states and myopathies; this might indicate cross-similar mechanisms between such dysfunctions and fat deposition in Wagyu breed. Animal models can be used not only for a better understanding of fat deposition in livestock, but also as models to an increased comprehension on molecular mechanisms behind human conditions. This revision underlies some of the complex molecular processes of fat deposition in animals.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1751-7311
17517311
Relation: http://www.sciencedirect.com/science/article/pii/S1751731115002992; https://doaj.org/toc/1751-7311
DOI: 10.1017/S1751731115002992
URL الوصول: https://doaj.org/article/eb3a8c49e5094942ad5edd2f83c7463f
رقم الأكسشن: edsdoj.b3a8c49e5094942ad5edd2f83c7463f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17517311
DOI:10.1017/S1751731115002992