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Reliability and responsiveness of the D12 and validity of its scores as a measure of dyspnoea severity in patients with rheumatoid arthritis-related interstitial lung disease

التفاصيل البيبلوغرافية
العنوان: Reliability and responsiveness of the D12 and validity of its scores as a measure of dyspnoea severity in patients with rheumatoid arthritis-related interstitial lung disease
المؤلفون: Jeffrey J Swigris, Sonye Danoff, Paul F Dellaripa, Joshua J Solomon, Tracy J Doyle
المصدر: BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
بيانات النشر: BMJ Publishing Group, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Diseases of the respiratory system
مصطلحات موضوعية: Medicine, Diseases of the respiratory system, RC705-779
الوصف: Background Interstitial lung disease due to rheumatoid arthritis (RA-ILD) affects a substantial minority of patients with RA, inducing life-altering symptoms, impairing quality of life (QOL) and forcing patients to confront the potential for shortened survival. Dyspnoea is the predominant respiratory symptom of RA-ILD and a strong driver of QOL impairment in patients with it. The D12 is a 12-item questionnaire that assesses the physical and affective components of dyspnoea. It was one of a battery of patient-reported outcomes used in the double-blind, placebo-controlled TRAIL 1 trial of pirfenidone for RA-ILD. There is little information on the reliability, validity or responsiveness of the D12 in RA-ILD.Methods In accordance with COSMIN (COnsensus-based Standards for the selection of health Measurement INstruments) methodology, we conducted analyses on data from the TRAIL 1 trial to assess the measurement properties of the D12.Results Internal consistency (α=0.95, 0.95, 0.95, 0.95 and 0.96 at baseline, 13, 26, 39 and 52 weeks) and test-retest reliability 0.85 (0.71 to 0.92) exceeded acceptability criteria. Well over the 75% benchmark of hypotheses (43/46=93%) around D12 measurement properties were confirmed. Known-groups validity was supported by significant differences between subgroups of patients with differing levels of dyspnoea (eg, St. George’s Respiratory Questionnaire (SGRQ) Activity score ≥50 vs
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2052-4439
Relation: https://bmjopenrespres.bmj.com/content/10/1/e001872.full; https://doaj.org/toc/2052-4439
DOI: 10.1136/bmjresp-2023-001872
URL الوصول: https://doaj.org/article/b3cca9f732844bb4b6b5c033330d1e74
رقم الأكسشن: edsdoj.b3cca9f732844bb4b6b5c033330d1e74
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20524439
DOI:10.1136/bmjresp-2023-001872