دورية أكاديمية
Radicality and safety of total mesopancreatic excision in pancreatoduodenectomy: a systematic review and meta-analysis
| العنوان: | Radicality and safety of total mesopancreatic excision in pancreatoduodenectomy: a systematic review and meta-analysis |
|---|---|
| المؤلفون: | Luís Felipe Leite da Silva, Marcos Belotto, Luiz F. Costa de Almeida, Júnior Samuel, Leonardo H. Pereira, Rafael Oliveira Albagli, Marcelo Sa de Araujo, Jose M. Ramia |
| المصدر: | World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-10 (2024) |
| بيانات النشر: | BMC, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Surgery LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | Pancreatoduodenectomy, Mesopancreas, Total mesopancreas excision, Meta-analysis, Systematic review, Surgery, RD1-811, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Abstract Background Pancreatic head cancer patients who undergo pancreatoduodenectomy (PD) often experience disease recurrence, frequently associated with a positive margin status (R1). Total mesopancreas excision (TMpE) has emerged as a potential approach to increase surgical radicality and minimize locoregional recurrence. However, its effectiveness and safety remain under evaluation. Methods We conducted a systematic review and meta-analysis to synthesize current evidence on TMpE outcomes. A systematic search of MEDLINE, EMBASE, Cochrane, and Web of Science databases was conducted up to March 2024 to identify studies comparing TMpE with standard pancreatoduodenectomy (sPD). The risk ratio (RR) or mean difference (MD) was pooled using a random effects model. Results From 452 studies identified, 9 studies with a total of 738 patients were included, with 361 (49%) undergoing TMpE. TMpE significantly improved the R0 resection rate (RR 1.24; 95% CI 1.11–1.38; P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1477-7819 |
| Relation: | https://doaj.org/toc/1477-7819 |
| DOI: | 10.1186/s12957-024-03495-2 |
| URL الوصول: | https://doaj.org/article/ab40891e270c4f8387bf7a7d74c435b4 |
| رقم الأكسشن: | edsdoj.b40891e270c4f8387bf7a7d74c435b4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 14777819 |
|---|---|
| DOI: | 10.1186/s12957-024-03495-2 |