دورية أكاديمية
Paraventricular hypothalamus mediates diurnal rhythm of metabolism
| العنوان: | Paraventricular hypothalamus mediates diurnal rhythm of metabolism |
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| المؤلفون: | Eun Ran Kim, Yuanzhong Xu, Ryan M. Cassidy, Yungang Lu, Yongjie Yang, Jinbin Tian, De-Pei Li, Rachel Van Drunen, Aleix Ribas-Latre, Zhao-Lin Cai, Mingshan Xue, Benjamin R. Arenkiel, Kristin Eckel-Mahan, Yong Xu, Qingchun Tong |
| المصدر: | Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
| بيانات النشر: | Nature Portfolio, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Science |
| مصطلحات موضوعية: | Science |
| الوصف: | Defective rhythmic metabolism is associated with high-fat diet feeding and obesity. The authors show that the clock gene BMAL1 drives paraventricular hypothalamic neuron activity via rhythmic GABAergic neurotransmission, and that this mediates diurnal metabolism and diet-induced obesity. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2041-1723 40434818 |
| Relation: | https://doaj.org/toc/2041-1723 |
| DOI: | 10.1038/s41467-020-17578-7 |
| URL الوصول: | https://doaj.org/article/b479012e40434818870fa48db8ae759a |
| رقم الأكسشن: | edsdoj.b479012e40434818870fa48db8ae759a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20411723 40434818 |
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| DOI: | 10.1038/s41467-020-17578-7 |