Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5

التفاصيل البيبلوغرافية
العنوان:	Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5
المؤلفون:	Sungjun Park, Seungwon Lee, Choong-Gu Lee, Guk Yeol Park, Hyebeen Hong, Jeon-Soo Lee, Young Min Kim, Sung Bae Lee, Daehee Hwang, Youn Soo Choi, John D. Fryer, Sin-Hyeog Im, Seung-Woo Lee, Yoontae Lee
المصدر:	Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
بيانات النشر:	Nature Portfolio, 2017.
سنة النشر:	2017
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Follicular helper T (TFH) cells promote germinal centre (GC) response for efficient generation of protective antibodies during humoral immunity. Here the authors show that deficiency of the translational repressor, Capicua/CIC, enhances TFH differentiation and GC responses potentially via the derepression of Etv5.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/ncomms16037
URL الوصول:	https://doaj.org/article/b60b97a6a56040e89b56ef95ec263afc
رقم الأكسشن:	edsdoj.b60b97a6a56040e89b56ef95ec263afc
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/ncomms16037