دورية أكاديمية
أعرض في EDS

Onset of pulmonary Epstein–Barr virus‐positive diffuse large B‐cell lymphoma in a patient with silicosis

التفاصيل البيبلوغرافية
العنوان: Onset of pulmonary Epstein–Barr virus‐positive diffuse large B‐cell lymphoma in a patient with silicosis
المؤلفون: Ryosuke Ogata, Hiroshi Soda, Yasuhiro Tanaka, Hiroaki Senju, Midori Shimada, Koki Yamashita, Shota Nakashima, Asuka Umemura, Masataka Yoshida, Takuya Hara, Saeko Jinnai, Keisuke Iwasaki, Yuichi Fukuda, Hiroyuki Yamaguchi, Hiroshi Mukae
المصدر: Thoracic Cancer, Vol 13, Iss 1, Pp 133-136 (2022)
بيانات النشر: Wiley, 2022.
سنة النشر: 2022
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: Epstein–Barr virus, immune cells, lymphoma, silicosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Abstract How Epstein–Barr virus (EBV)‐positive diffuse large B‐cell lymphoma (DLBCL) occasionally occurs following chronic inflammation remains to be elucidated. The case of a 57‐year‐old man who developed pulmonary EBV‐positive DLBCL from underlying silicosis lesions is presented. Immunohistochemical examination of the resected silicosis lesions showed predominant helper T cells and M1/M2 macrophages, with a lack of B cells, regulatory T cells, and resident memory T cells. Two years later, EBV‐positive DLBCL emerged unexpectedly from the silicosis. The imbalance of the immune cells in the microenvironment, at least in part, may help explain how chronic inflammation contributes to EBV‐positive DLBCL.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1759-7714
1759-7706
Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714
DOI: 10.1111/1759-7714.14250
URL الوصول: https://doaj.org/article/b61746868d1048ba9d655c3efbd480dc
رقم الأكسشن: edsdoj.b61746868d1048ba9d655c3efbd480dc
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17597714
17597706
DOI:10.1111/1759-7714.14250