دورية أكاديمية
Effect of antihistamine-releasing contact lenses on ocular symptoms and treatment behavior in patients with seasonal allergic conjunctivitis: A retrospective study
| العنوان: | Effect of antihistamine-releasing contact lenses on ocular symptoms and treatment behavior in patients with seasonal allergic conjunctivitis: A retrospective study |
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| المؤلفون: | Kenta Fujio, Jaemyoung Sung, Kunihiko Hirosawa, Masahiro Yamaguchi, Hiroshi Toshida, Keiji Inagaki, Gaku Ishida, Motozumi Itoi, Kazushige Sado, Hiroo Hayatsu, Hirayama Nobutaka, Junji Ono, Hidetaka Taniguchi, Masao Iwagami, Ken Nagino, Yuichi Okumura, Akie Midorikawa-Inomata, Yasutsugu Akasaki, Tianxiang Huang, Yuki Morooka, Tomoko Okuyama, Shintaro Nakao, Akira Murakami, Hiroyuki Kobayashi, Takenori Inomata |
| المصدر: | Heliyon, Vol 10, Iss 13, Pp e33385- (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Science (General) LCC:Social sciences (General) |
| مصطلحات موضوعية: | Allergic conjunctivitis, Contact lens, Drug delivery, Hay fever, Pollinosis, Science (General), Q1-390, Social sciences (General), H1-99 |
| الوصف: | Purpose: This study aimed to compare subjective allergic conjunctivitis symptoms and anti-allergic eye drop use patterns between antihistamine-releasing contact lens users and daily disposable soft contact lens users during Japan's hay fever season. Methods: This web-based retrospective cohort study included daily disposable soft contact lens or antihistamine-releasing contact lens users with a history of seasonal allergic conjunctivitis who regularly used daily disposable soft contact lenses since the previous year. The total ocular symptom score (range 0–20) based on 5-item questionnaire scores and time from the start of the hay fever season to the initiation of anti-allergic eye drop treatment were compared between antihistamine-releasing contact lens users and daily disposable soft contact lens users. Results: The study included 24 participants: 17 using daily disposable soft contact lenses and 7 using antihistamine-releasing contact lenses. Antihistamine-releasing contact lens users experienced a greater reduction in total ocular symptom score from 2021 to 2022 compared with daily disposable soft contact lens users (mean total ocular symptom score [standard deviation]: daily disposable soft contact lens: −0.65 [1.4], antihistamine-releasing contact lens: −4.7 [3.6]; n = 24; Mann–Whitney U test, P = 0.010). Fourteen daily disposable soft contact lens users and five antihistamine-releasing contact lens users eventually required anti-allergic eye drops. Kaplan–Meier analysis revealed a significant delay in the initiation of anti-allergic eye drop treatment among those using antihistamine-releasing contact lenses compared with those using daily disposable soft contact lenses (median days, daily disposable soft contact lenses: 19 days, antihistamine-releasing contact lens: 57 days; n = 24; log-rank test, P = 0.045). Conclusions: Antihistamine-releasing contact lenses can potentially mitigate worsening ocular allergic responses during the hay fever season when used appropriately as a preventive measure. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2405-8440 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2405844024094167; https://doaj.org/toc/2405-8440 |
| DOI: | 10.1016/j.heliyon.2024.e33385 |
| URL الوصول: | https://doaj.org/article/b63e2e4b7b314eccb0764b6c01ed3cc4 |
| رقم الأكسشن: | edsdoj.b63e2e4b7b314eccb0764b6c01ed3cc4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24058440 |
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| DOI: | 10.1016/j.heliyon.2024.e33385 |