دورية أكاديمية
Vaccine development for syphilis
| العنوان: | Vaccine development for syphilis |
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| المؤلفون: | Karen V. Lithgow, Caroline E. Cameron |
| المصدر: | Expert Review of Vaccines, Vol 16, Iss 1, Pp 37-44 (2017) |
| بيانات النشر: | Taylor & Francis Group, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Internal medicine |
| مصطلحات موضوعية: | syphilis, congenital syphilis, hiv co-infection, cross-protection, cellular immunity, humoral immunity, men who have sex with men, vaccine, Internal medicine, RC31-1245 |
| الوصف: | Introduction: Syphilis, caused by the spirochete Treponema pallidum subspecies pallidum, continues to be a globally prevalent disease despite remaining susceptible to penicillin treatment. Syphilis vaccine development is a viable preventative approach that will serve to complement public health-oriented syphilis prevention, screening and treatment initiatives to deliver a two-pronged approach to stemming disease spread worldwide. Areas covered: This article provides an overview of the need for development of a syphilis vaccine, summarizes significant information that has been garnered from prior syphilis vaccine studies, discusses the critical aspects of infection that would have to be targeted by a syphilis vaccine, and presents the current understanding within the field of the correlates of protection needed to be achieved through vaccination. Expert commentary: Syphilis vaccine development should be considered a priority by industry, regulatory and funding agencies, and should be appropriately promoted and supported. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1476-0584 1744-8395 14760584 62459775 |
| Relation: | https://doaj.org/toc/1476-0584; https://doaj.org/toc/1744-8395 |
| DOI: | 10.1080/14760584.2016.1203262 |
| URL الوصول: | https://doaj.org/article/b7a47d87a2154845b3a9622e62459775 |
| رقم الأكسشن: | edsdoj.b7a47d87a2154845b3a9622e62459775 |
| قاعدة البيانات: | Directory of Open Access Journals |
PDF full text from Publisher | تدمد: | 14760584 17448395 62459775 |
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| DOI: | 10.1080/14760584.2016.1203262 |