التفاصيل البيبلوغرافية
العنوان:
Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia
المؤلفون:
Yotaro Ochi , Kenichi Yoshida , Ying-Jung Huang , Ming-Chung Kuo , Yasuhito Nannya , Ko Sasaki , Kinuko Mitani , Noriko Hosoya , Nobuhiro Hiramoto , Takayuki Ishikawa , Susan Branford , Naranie Shanmuganathan , Kazuma Ohyashiki , Naoto Takahashi , Tomoiku Takaku , Shun Tsuchiya , Nobuhiro Kanemura , Nobuhiko Nakamura , Yasunori Ueda , Satoshi Yoshihara , Rabindranath Bera , Yusuke Shiozawa , Lanying Zhao , June Takeda , Yosaku Watatani , Rurika Okuda , Hideki Makishima , Yuichi Shiraishi , Kenichi Chiba , Hiroko Tanaka , Masashi Sanada , Akifumi Takaori-Kondo , Satoru Miyano , Seishi Ogawa , Lee-Yung Shih
المصدر:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
بيانات النشر:
Nature Portfolio, 2021.
سنة النشر:
2021
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
In chronic myeloid leukaemia (CML), the drivers of blast crisis and resistance to tyrosine kinase inhibitors are not fully characterised. Here, the authors analyse a cohort of CML samples with genomic technologies and find that at least one driver alteration is associated with progression and worse prognosis.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
Relation:
https://doaj.org/toc/2041-1723
DOI:
10.1038/s41467-021-23097-w
URL الوصول:
https://doaj.org/article/b8463e0b7aef42f9abaf389f4f41e7bd
رقم الأكسشن:
edsdoj.b8463e0b7aef42f9abaf389f4f41e7bd
قاعدة البيانات:
Directory of Open Access Journals
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