دورية أكاديمية
Heterogeneity of Mycobacterium tuberculosis drug resistance in respect of pharmacokinetics of anti-tuberculosis drugs as a basis for individual treatment regimen
| العنوان: | Heterogeneity of Mycobacterium tuberculosis drug resistance in respect of pharmacokinetics of anti-tuberculosis drugs as a basis for individual treatment regimen |
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| المؤلفون: | S. A. Popov, T. P. Sabgaida, G. N. Mozkokina, A. V. Kuzmin, N. V. Stavitskaya |
| المصدر: | Туберкулез и болезни лёгких, Vol 0, Iss 4, Pp 18-23 (2015) |
| بيانات النشر: | New Terra Publishing House, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Diseases of the respiratory system |
| مصطلحات موضوعية: | туберкулез, персонифицированные режимы лечения, лекарственная устойчивость m. tuberculosis, минимальные ингибирующие концентрации противотуберкулезных препаратов, типы ацетилирования, фармакокинетика, фармакогенетика, Diseases of the respiratory system, RC705-779 |
| الوصف: | This article analyzes the ways of treatment efficacy enhancement in drug resistant tuberculosis patients through transfer to the individual treatment regimens basing on the objective laboratory data. The presence of M. tuberculosis population heterogeneity has been demonstrated as per the degree of resistance to different drugs relating individual pharmacokinetic features of the patients. The article includes discussion of technical opportunities for the implementation of such approach, the need for detail evaluation of the germ resistance and limits of effective action of anti-tuberculosis drugs related to their pharmacokinetics and pharmacogenetics. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 2075-1230 2542-1506 04401999 |
| Relation: | https://www.tibl-journal.com/jour/article/view/356; https://doaj.org/toc/2075-1230; https://doaj.org/toc/2542-1506 |
| DOI: | 10.21292/2075-1230-2015-0-4-18-23 |
| URL الوصول: | https://doaj.org/article/b85c40754bc0440199978b5bc1c74ebf |
| رقم الأكسشن: | edsdoj.b85c40754bc0440199978b5bc1c74ebf |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20751230 25421506 04401999 |
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| DOI: | 10.21292/2075-1230-2015-0-4-18-23 |