دورية أكاديمية
A review on gold nanoparticles as an innovative therapeutic cue in bone tissue engineering: Prospects and future clinical applications
| العنوان: | A review on gold nanoparticles as an innovative therapeutic cue in bone tissue engineering: Prospects and future clinical applications |
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| المؤلفون: | Dae Hyeok Yang, Haram Nah, Donghyun Lee, Sung Jun Min, Seulki Park, Sang-Hyun An, Jianxin Wang, Huining He, Kyu-Sun Choi, Wan-Kyu Ko, Jae Seo Lee, Il Keun Kwon, Sang Jin Lee, Dong Nyoung Heo |
| المصدر: | Materials Today Bio, Vol 26, Iss , Pp 101016- (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine (General) LCC:Biology (General) |
| مصطلحات موضوعية: | Medicine (General), R5-920, Biology (General), QH301-705.5 |
| الوصف: | Bone damage is a complex orthopedic problem primarily caused by trauma, cancer, or bacterial infection of bone tissue. Clinical care management for bone damage remains a significant clinical challenge and there is a growing need for more advanced bone therapy options. Nanotechnology has been widely explored in the field of orthopedic therapy for the treatment of a severe bone disease. Among nanomaterials, gold nanoparticles (GNPs) along with other biomaterials are emerging as a new paradigm for treatment with excellent potential for bone tissue engineering and regenerative medicine applications. In recent years, a great deal of research has focused on demonstrating the potential for GNPs to provide for enhancement of osteogenesis, reduction of osteoclastogenesis/osteomyelitis, and treatment of bone cancer. This review details the latest understandings in regards to GNPs based therapeutic systems, mechanisms, and the applications of GNPs against various bone disorders. The present review aims to summarize i) the mechanisms of GNPs in bone tissue remodeling, ii) preparation methods of GNPs, and iii) functionalization of GNPs and its decoration on biomaterials as a delivery vehicle in a specific bone tissue engineering for future clinical application. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2590-0064 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2590006424000759; https://doaj.org/toc/2590-0064 |
| DOI: | 10.1016/j.mtbio.2024.101016 |
| URL الوصول: | https://doaj.org/article/b85c422dd1294da183c58ef3fe3f7729 |
| رقم الأكسشن: | edsdoj.b85c422dd1294da183c58ef3fe3f7729 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 25900064 |
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| DOI: | 10.1016/j.mtbio.2024.101016 |