دورية أكاديمية
Immunopathogenesis and neurological manifestations associated to HTLV-1 infection
| العنوان: | Immunopathogenesis and neurological manifestations associated to HTLV-1 infection |
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| المؤلفون: | Anselmo Souza, Davi Tanajura, Cristina Toledo-Cornell, Silvane Santos, Edgar Marcelino de Carvalho |
| المصدر: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 5, Pp 545-552 (2012) |
| بيانات النشر: | Sociedade Brasileira de Medicina Tropical (SBMT), 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Arctic medicine. Tropical medicine |
| مصطلحات موضوعية: | HTLV-1, Resposta imune, HAM/TSP, Doença neurológica, Arctic medicine. Tropical medicine, RC955-962 |
| الوصف: | The human T lymphotropic virus type-1 (HTLV-1) was the first human retrovirus identified. The virus is transmitted through sexual intercourse, blood transfusion, sharing of contaminated needles or syringes and from mother to child, mainly through breastfeeding. In addition to the well-known association between HTLV-1 and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), several diseases and neurologic manifestations have been associated with the virus. This review was conducted through a PubMed search of the terms HTLV-1, immune response and neurological diseases. Emphasis was given to the most recent data regarding pathogenesis and clinical manifestations of HTLV-1 infection. The aim of the review is to analyze the immune response and the variety of neurological manifestations associated to HTLV-1 infection. A total of 102 articles were reviewed. The literature shows that a large percentage of HTLV-1 infected individuals have others neurological symptoms than HAM/TSP. Increased understanding of these numerous others clinical manifestations associated to the virus than adult T cell leukemia/lymphoma (ATLL) and HAM/TSP has challenged the view that HTLV-1 is a low morbidity infection. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-9849 0037-8682 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000500002&lng=en&tlng=en; https://doaj.org/toc/1678-9849 |
| DOI: | 10.1590/S0037-86822012000500002 |
| URL الوصول: | https://doaj.org/article/b9c0068059ba47ba80720edbf1532f7d |
| رقم الأكسشن: | edsdoj.b9c0068059ba47ba80720edbf1532f7d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16789849 00378682 |
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| DOI: | 10.1590/S0037-86822012000500002 |