دورية أكاديمية
Comparing the impact of chronic energy restriction and vitamin E supplementation on the behavior of adult rats
العنوان: | Comparing the impact of chronic energy restriction and vitamin E supplementation on the behavior of adult rats |
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المؤلفون: | Derlange B Diniz, Suzana L de Oliveira, Liana L Melo, Jaime Amaya-Farfan |
المصدر: | Archivos Latinoamericanos de Nutrición, Vol 59, Iss 3, Pp 287-295 |
بيانات النشر: | Sociedad Latinoamericana de Nutrición. |
المجموعة: | LCC:Nutrition. Foods and food supply LCC:Biology (General) |
مصطلحات موضوعية: | dieta, comportamiento, restricción energética, suplementación con vitamina e, dieta antioxidante, Nutrition. Foods and food supply, TX341-641, Biology (General), QH301-705.5 |
الوصف: | The purpose of this work was to investigate the influence of energy restriction and vitamin E supplementation on memory, learning, anxiety and spontaneous locomotion in adult rats. Three-month old male Wistar rats were grouped according to diet: Control (AIN 93-M; n=18), Supplemented (AIN 93-M + 1425 IU all-rac-α-tocopheryl acetate/kg diet; n=22) and Restricted (AIN 93-M with 30% reduction in carbohydrate energy; n=23). Sixteen weeks after, the passive avoidance (PA), elevated plus-maze (EPM) and open field (OF) tests were applied. In the EPM test, the behavioral profile of the supplemented group was characterized by a lower frequency of entries into the open arms (P < 0,026), whereas the restricted group showed a lower frequency of head dipping (P < 0,003). The ratio between the time span of the shocks and the number of attempts were larger for the supplemented than for the non-supplemented animals (P = 0,0474), thus suggesting a delay in learning in the PA test. Taken together, these results suggest that a long-term combination of carbohydrate energy restriction in rats should not cause negative behavioral alterations. Compared with vitamin E supplementation, the restricted diet performed equally or better in rats as an alternate antioxidant diet. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English Spanish; Castilian Portuguese |
تدمد: | 0004-0622 |
Relation: | http://www.scielo.org.ve/scielo.php?script=sci_arttext&pid=S0004-06222009000300009&lng=en&tlng=en; https://doaj.org/toc/0004-0622 |
URL الوصول: | https://doaj.org/article/cba4fdd6fddd4aa7805eca4b4172d1d2 |
رقم الأكسشن: | edsdoj.ba4fdd6fddd4aa7805eca4b4172d1d2 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 00040622 |
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