دورية أكاديمية
Synthesis of silver nanoparticle-decorated hydroxyapatite nanocomposite with combined bioactivity and antibacterial properties
| العنوان: | Synthesis of silver nanoparticle-decorated hydroxyapatite nanocomposite with combined bioactivity and antibacterial properties |
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| المؤلفون: | Soo-Ling Bee, Yazmin Bustami, A. Ul-Hamid, Keemi Lim, Z. A. Abdul Hamid |
| المصدر: | Journal of Materials Science: Materials in Medicine, Vol 32, Iss 9, Pp 1-12 (2021) |
| بيانات النشر: | Springer, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Materials of engineering and construction. Mechanics of materials LCC:Medical technology |
| مصطلحات موضوعية: | Materials of engineering and construction. Mechanics of materials, TA401-492, Medical technology, R855-855.5 |
| الوصف: | Abstract Combination of bioactive material such as hydroxyapatite (HAp) with antibacterial agents would have great potential to be used as bone implant materials to avert possible bacterial infection that can lead to implant-associated diseases. The present study aimed to develop an antibacterial silver nanoparticle-decorated hydroxyapatite (HAp/AgNPs) nanocomposite using chemical reduction and thermal calcination approaches. In this work, natural HAp that was extracted from chicken bone wastes is used as support matrix for the deposition of silver nanoparticles (AgNPs) to produce HAp/AgNPs nanocomposite. XRD, FESEM-EDX, HRTEM, and XPS analyses confirmed that spherical AgNPs were successfully synthesized and deposited on the surface of HAp particles, and the amount of AgNPs adhered on the HAp surface increased with increasing AgNO3 concentration used. The synthesized HAp/AgNPs nanocomposites demonstrated strong antibacterial activity against Staphylococcus aureus bacteria, where the antibacterial efficiency is relied on the amount and size of deposited AgNPs. In addition, the in vitro bioactivity examination in Hank’s balanced salt solution showed that more apatite were grown on the surface of HAp/AgNPs nanocomposite when AgNO3 concentration used >1 wt.%. Such nanocomposite with enhanced bioactivity and antibacterial properties emerged as a promising biomaterial to be applied for dentistry and orthopedic implantology. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0957-4530 1573-4838 |
| Relation: | https://doaj.org/toc/0957-4530; https://doaj.org/toc/1573-4838 |
| DOI: | 10.1007/s10856-021-06590-y |
| URL الوصول: | https://doaj.org/article/aeba614c83504b398e8f3c8686b39de0 |
| رقم الأكسشن: | edsdoj.ba614c83504b398e8f3c8686b39de0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 09574530 15734838 |
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| DOI: | 10.1007/s10856-021-06590-y |