دورية أكاديمية
Les rôles physiologiques majeurs exercés par les acides gras polyinsaturés (AGPI)
| العنوان: | Les rôles physiologiques majeurs exercés par les acides gras polyinsaturés (AGPI) |
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| المؤلفون: | Guesnet Philippe, Alessandri Jean-Marc, Astorg Pierre, Pifferi Fabien, Lavialle Monique |
| المصدر: | Oléagineux, Corps gras, Lipides, Vol 12, Iss 5-6, Pp 333-343 (2005) |
| بيانات النشر: | EDP Sciences, 2005. |
| سنة النشر: | 2005 |
| المجموعة: | LCC:Oils, fats, and waxes |
| مصطلحات موضوعية: | arachidonic acid, docosahexaenoic acid, eicosapentaenoic acid, physiological functions, polyunsaturated fatty acids, cell membranes, Oils, fats, and waxes, TP670-699 |
| الوصف: | Polyunsaturated fatty acids (PUFAs) are essential nutrients for mammals and the human species, and belong to either of two distinct and not interconvertible series, omega 6 and omega 3. The metabolic precursors of these two series, linoleic and α-linolenic acids respectively, are the dietary essential fatty acids. These two fatty acids, once absorbed, lead to the specific synthesis and incorporation in practically all cell membranes of long-chain active PUFA derivatives such as arachidonic acid for the omega 6 series and eicosapentaenoic and docosahexaenoic acids for the omega 3 series. Long-chain PUFA affect many physiological functions because they are essential factors in many cellular functions by regulating physical properties of membranes, eicosanoid signalling and gene expression of encoding enzymes of triglyceride storage and fatty acid oxidation. The consumption of omega 6 and omega 3 fatty acids in equilibrated proportions could be crucial in the regulation of cellular physiology and in the prevention of pathologies such as cardiovascular, autoimmune and inflammatory diseases, diabetes and obesity, certain neuropsychiatric affections, etc. Indeed, the dietary intake of omega 3 fatty acid (α-linolenate and also docosahexaenoate) are crucial parameters in the development of retinal and neural function in the newborn infant. On the other hand, a high ratio of omega6/omega 3 fatty acids in cell membranes due to an excessive consumption of omega 6 fatty acids and a relative omega 3 fatty acid deficiency, may promote the pathogenesis of several diseases, including cardiovascular diseases, metabolic syndrome, inflammatory disorders and obesity. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English French |
| تدمد: | 1258-8210 1950-697X |
| Relation: | https://doaj.org/toc/1258-8210; https://doaj.org/toc/1950-697X |
| DOI: | 10.1051/ocl.2005.0333 |
| URL الوصول: | https://doaj.org/article/bb25af932d6844de818f6fae9eefacb0 |
| رقم الأكسشن: | edsdoj.bb25af932d6844de818f6fae9eefacb0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 12588210 1950697X |
|---|---|
| DOI: | 10.1051/ocl.2005.0333 |