دورية أكاديمية
Evidence for Directed Evolution of Larger Size Motif in Arabidopsis thaliana Genome
| العنوان: | Evidence for Directed Evolution of Larger Size Motif in Arabidopsis thaliana Genome |
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| المؤلفون: | Rajesh Mehrotra, Amit Yadav, Purva Bhalothia, Ratna Karan, Sandhya Mehrotra |
| المصدر: | The Scientific World Journal, Vol 2012 (2012) |
| بيانات النشر: | Hindawi Limited, 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Technology LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Technology, Medicine, Science |
| الوصف: | Transcription control of gene expression depends on a variety of interactions mediated by the core promoter region, sequence specific DNA-binding proteins, and their cognate promoter elements. The prominent group of cis acting elements in plants contains an ACGT core. The cis element with this core has been shown to be involved in abscisic acid, salicylic acid, and light response. In this study, genome-wide comparison of the frequency of occurrence of two ACGT elements without any spacers as well as those separated by spacers of different length was carried out. In the first step, the frequency of occurrence of the cis element sequences across the whole genome was determined by using BLAST tool. In another approach the spacer sequence was randomized before making the query. As expected, the sequence ACGTACGT had maximum occurrence in Arabidopsis thaliana genome. As we increased the spacer length, one nucleotide at a time, the probability of its occurrence in genome decreased. This trend continued until an unexpectedly sharp rise in frequency of (ACGT)N25(ACGT). The observation of higher probability of bigger size motif suggests its directed evolution in Arabidopsis thaliana genome. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1537-744X |
| Relation: | https://doaj.org/toc/1537-744X |
| DOI: | 10.1100/2012/983528 |
| URL الوصول: | https://doaj.org/article/abb4b8b0f6804855af4ed788be00364b |
| رقم الأكسشن: | edsdoj.bb4b8b0f6804855af4ed788be00364b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1537744X |
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| DOI: | 10.1100/2012/983528 |