دورية أكاديمية
Regulatory T cells isolated from endometriotic peritoneal fluid express a different number of Toll-like receptors
| العنوان: | Regulatory T cells isolated from endometriotic peritoneal fluid express a different number of Toll-like receptors |
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| المؤلفون: | Camila Hernandes, Bárbara Yasmin Gueuvoghlanian-Silva, Vitor Ulisses Monnaka, Natalia Mazini Ribeiro, Welbert de Oliveira Pereira, Sérgio Podgaec |
| المصدر: | Einstein (São Paulo), Vol 18 (2020) |
| بيانات النشر: | Instituto Israelita de Ensino e Pesquisa Albert Einstein, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | T-lymphocytes, regulatory, Toll-like receptors, Immune system, Endometriosis, Medicine |
| الوصف: | ABSTRACT Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis. Methods Regulatory T cells were isolated from peritoneal fluid of women with and without endometriosis, collected during surgery, and mRNA was extracted for analysis of Toll-like receptors expression by reverse-transcriptase polymerase chain reaction. Results Patients with endometriosis presented regulatory T cells expressing a larger number and variety of Toll-like receptors when compared to regulatory T cells from patients in the Control Group. Toll-like receptor-1 and Toll-like receptor-2 in regulatory T cells were expressed in both groups. All other expressed Toll-like receptors types were only found in regulatory T cells from the Endometriosis Group. Conclusion Patients with endometriosis had peritoneal regulatory T cells expressing various Toll-like receptors types. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 2317-6385 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082020000100247&tlng=en; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082020000100247&tlng=pt; https://doaj.org/toc/2317-6385 |
| DOI: | 10.31744/einstein_journal/2020ao5294 |
| URL الوصول: | https://doaj.org/article/bc1a263ba60745b4b495c79c4488e2aa |
| رقم الأكسشن: | edsdoj.bc1a263ba60745b4b495c79c4488e2aa |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23176385 |
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| DOI: | 10.31744/einstein_journal/2020ao5294 |