دورية أكاديمية
Antibiotic-associated diarrhea in children: how to identify, what to do and how to treat?
| العنوان: | Antibiotic-associated diarrhea in children: how to identify, what to do and how to treat? |
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| المؤلفون: | I. N. Zakharova, I. V. Berezhnaya, E. B. Mumladze |
| المصدر: | Медицинский совет, Vol 1, Iss 1, Pp 78-89 (2016) |
| بيانات النشر: | Remedium Group LLC, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | желудочно-кишечный тракт, антибиотики, антибиотик-ассоциированная диарея, псевдомембранозный колит, дети, экоантибиотики, экоклав, микробиота, c. difficile-инфекция, токсины а и в, профилактика, пробиотики, лечение, gastrointestinal tract, antibiotics, antibiotic-associated diarrhea, pseudomembranous colitis, children, eco-antibiotics, ecoclav, microbiota, c. difficile infection, c. difficile toxins a and b, prevention, probiotics, treatment, Medicine |
| الوصف: | Rational antibiotic therapy is one of the most important components in the treatment of children with various infectious and inflammatory diseases. However, wide and sometimes unjustified use of AB in pediatric practice often leads to the development of a variety of complications. Children receiveing AB, especially during the first 5 years of life, are at a very high risk of developing antibiotic-associated diarrhea (AAD) which manifests itself in three or more episodes of unformed stools for two or more consecutive days or for 8 weeks after withdrawal. The most relevant pathogen of AAD is C. difficile which, according to various data, causes from 10 to 25% of AAD cases and 90 to 100% of all cases of pseudomembranous colitis (PMC). Given the high probability of developing dangerous complications such as PMC, special attention should be paid to the prevention of the infection associated with C. difficile by reducing the frequency of uncontrolled and unjustified use of AB. A new generation of eco-antibiotics can be recommended which allow to maintain diversity of the intestinal microbiota and are less likely to cause complications. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 2079-701X 2658-5790 |
| Relation: | https://www.med-sovet.pro/jour/article/view/14; https://doaj.org/toc/2079-701X; https://doaj.org/toc/2658-5790 |
| DOI: | 10.21518/2079-701X-2016-1-78-89 |
| URL الوصول: | https://doaj.org/article/bc88df6bd40c48828c317777f733d2b1 |
| رقم الأكسشن: | edsdoj.bc88df6bd40c48828c317777f733d2b1 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2079701X 26585790 |
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| DOI: | 10.21518/2079-701X-2016-1-78-89 |