دورية أكاديمية
Severity predictors for multisystemic inflammatory syndrome in children after SARS-CoV-2 infection in Vietnam
| العنوان: | Severity predictors for multisystemic inflammatory syndrome in children after SARS-CoV-2 infection in Vietnam |
|---|---|
| المؤلفون: | Dien. M. Tran, Dem. V. Pham, Tung. V. Cao, Canh. N. Hoang, Ha. T. T. Nguyen, Giang. D. Nguyen, Cuong. N. Le, Quan. Q. Thieu, Tuan. A. Ta, Hung. V. Dau, Chi. Q. Le, Quang. H. Le, Nghiem. T. Luong, Mai. T. Tran, Phu. H. Nguyen, Nhung. T. Nguyen, Phuc. H. Phan |
| المصدر: | Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024) |
| بيانات النشر: | Nature Portfolio, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Multisystemic inflammatory syndrome in children, MIS-C, Severity, Shock, SARS-CoV-2, Medicine, Science |
| الوصف: | Abstract Multisystemic inflammatory syndrome in children (MIS-C) might manifest in a broad spectrum of clinical scenarios, ranging from mild features to multi-organ dysfunction and mortality. However, this novel entity has a heterogenicity of data regarding prognostic factors associated with severe outcomes. The present study aimed to identify independent predictors for severity by using multivariate regression models. A total of 391 patients (255 boys and 136 girls) were admitted to Vietnam National Children’s Hospital from January 2022 to June 2023. The median age was 85 (range: 2–188) months, and only 12 (3.1%) patients had comorbidities. 161 (41.2%) patients required PICU admission, and the median PICU LOS was 4 (2–7) days. We observed independent factors related to PICU admission, including CRP $$\ge $$ ≥ 50 (mg/L) (OR 2.52, 95% CI 1.39–4.56, p = 0.002), albumin $$\le $$ ≤ 30 (g/L) (OR 3.18, 95% CI 1.63–6.02, p = 0.001), absolute lymphocyte count $$\le $$ ≤ 2 (× 109/L) (OR 2.18, 95% CI 1.29–3.71, p = 0.004), ferritin ≥ 300 (ng/mL) (OR 2.35, 95% CI 1.38–4.01), p = 0.002), and LVEF |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-024-66891-4 |
| URL الوصول: | https://doaj.org/article/bcb648e31ad548c8a9c63da9ae09a086 |
| رقم الأكسشن: | edsdoj.bcb648e31ad548c8a9c63da9ae09a086 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20452322 |
|---|---|
| DOI: | 10.1038/s41598-024-66891-4 |