دورية أكاديمية
Experimental Tools to Study Molecular Recognition within the Nanoparticle Corona
| العنوان: | Experimental Tools to Study Molecular Recognition within the Nanoparticle Corona |
|---|---|
| المؤلفون: | Markita P. Landry, Sebastian Kruss, Justin T. Nelson, Gili Bisker, Nicole M. Iverson, Nigel F. Reuel, Michael S. Strano |
| المصدر: | Sensors, Vol 14, Iss 9, Pp 16196-16211 (2014) |
| بيانات النشر: | MDPI AG, 2014. |
| سنة النشر: | 2014 |
| المجموعة: | LCC:Chemical technology |
| مصطلحات موضوعية: | optical sensors, molecular recognition, fluorescence, single-molecule microscopy, neurotransmitters, corona phase, carbon nanotubes, Chemical technology, TP1-1185 |
| الوصف: | Advancements in optical nanosensor development have enabled the design of sensors using synthetic molecular recognition elements through a recently developed method called Corona Phase Molecular Recognition (CoPhMoRe). The synthetic sensors resulting from these design principles are highly selective for specific analytes, and demonstrate remarkable stability for use under a variety of conditions. An essential element of nanosensor development hinges on the ability to understand the interface between nanoparticles and the associated corona phase surrounding the nanosensor, an environment outside of the range of traditional characterization tools, such as NMR. This review discusses the need for new strategies and instrumentation to study the nanoparticle corona, operating in both in vitro and in vivo environments. Approaches to instrumentation must have the capacity to concurrently monitor nanosensor operation and the molecular changes in the corona phase. A detailed overview of new tools for the understanding of CoPhMoRe mechanisms is provided for future applications. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1424-8220 50448080 |
| Relation: | http://www.mdpi.com/1424-8220/14/9/16196; https://doaj.org/toc/1424-8220 |
| DOI: | 10.3390/s140916196 |
| URL الوصول: | https://doaj.org/article/bd0925d8fb50448080a2ac04b0955844 |
| رقم الأكسشن: | edsdoj.bd0925d8fb50448080a2ac04b0955844 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14248220 50448080 |
|---|---|
| DOI: | 10.3390/s140916196 |