دورية أكاديمية
The frequency of ophthalmologic manifestations of granulomatosis with polyangiitis (Wegener’s) and their relationship to systemic diseases
| العنوان: | The frequency of ophthalmologic manifestations of granulomatosis with polyangiitis (Wegener’s) and their relationship to systemic diseases |
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| المؤلفون: | D S Ismailova, P I Novikov, Ya O Grusha, Yu V Abramova, N M Bulanov, E A Makarov |
| المصدر: | Терапевтический архив, Vol 89, Iss 5, Pp 69-73 (2017) |
| بيانات النشر: | "Consilium Medicum" Publishing house, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | granulomatosis with polyangiitis, wegener’s granulomatosis, orbit, scleritis, antineutrophil cytoplasmic antibody-associated vasculitis, ophthalmic manifestations, Medicine |
| الوصف: | Aim. To estimate the frequency of lesions in the organ of vision in granulomatosis with polyangiitis (GPA) (Wegener’s) and to determine their relationship to systemic diseases. Subjects and methods. The retrospective study enrolled 218 patients followed up at the E.M. Tareyev Clinic of Nephrology, Internal and Occupational Diseases, with a diagnosis of GPA. The frequency and association of ophthalmic manifestations with systemic involvement were statistically analyzed using PASW Statistics 18. Results. The organ of vision was impaired in 48.1% of the patients with GPA. The most common manifestations were orbital space-occupying lesion (22.9%), conjunctivitis/episcleritis (14.7%), dacryocystitis (6.0%), and scleritis (4.6%). Orbital space-occupying lesions occurred more frequently in the local type of the disease (p=0.0003), and, on the contrary, the involvement of the conjunctiva and eyeball was seen in patients with the systemic types of GPA (p=0.02). Conclusion. The findings may suggest that the orbital lesion is an independent manifestation of GPA, which develops more commonly in its local type. Conjunctivitis/episcleritis is, on the contrary, more frequently seen in the active phase of the disease and generally in the involvement of other organs and systems. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 0040-3660 2309-5342 20178956 |
| Relation: | https://ter-arkhiv.ru/0040-3660/article/viewFile/32222/pdf; https://doaj.org/toc/0040-3660; https://doaj.org/toc/2309-5342 |
| DOI: | 10.17116/terarkh201789569-73 |
| URL الوصول: | https://doaj.org/article/bd3dc5e6a66d4b8696f1e6c53c50a5cb |
| رقم الأكسشن: | edsdoj.bd3dc5e6a66d4b8696f1e6c53c50a5cb |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 00403660 23095342 20178956 |
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| DOI: | 10.17116/terarkh201789569-73 |