دورية أكاديمية
Integrated chromatin accessibility and DNA methylation analysis to reveal the critical epigenetic modification and regulatory mechanism in gonadal differentiation of the sequentially hermaphroditic fish, Monopterus albus
| العنوان: | Integrated chromatin accessibility and DNA methylation analysis to reveal the critical epigenetic modification and regulatory mechanism in gonadal differentiation of the sequentially hermaphroditic fish, Monopterus albus |
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| المؤلفون: | Qiaomu Hu, Zitong Lian, Xueping Xia, Haifeng Tian, Zhong Li |
| المصدر: | Biology of Sex Differences, Vol 13, Iss 1, Pp 1-15 (2022) |
| بيانات النشر: | BMC, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine LCC:Physiology |
| مصطلحات موضوعية: | Sex reversal, Monopterus albus, DNA methylation, Chromatin accessibility, Epigenetic modification, Medicine, Physiology, QP1-981 |
| الوصف: | Highlights DNA methylation modification plays a more crucial role than chromatin accessibility in gonad development. DNA methylation in the transcription start site plays a key role in gonad development. DNA methylation of the plastin-2 promoter inhibited gene expression. Plastin-2 is positively regulated by dmrt1 while negatively regulated by foxl2. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2042-6410 |
| Relation: | https://doaj.org/toc/2042-6410 |
| DOI: | 10.1186/s13293-022-00484-6 |
| URL الوصول: | https://doaj.org/article/dbd7179683ee44b8ada5c77f9e046a08 |
| رقم الأكسشن: | edsdoj.bd7179683ee44b8ada5c77f9e046a08 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20426410 |
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| DOI: | 10.1186/s13293-022-00484-6 |