دورية أكاديمية
A couple of the first cousins born with hypotonia and maternal polyhydramnios
| العنوان: | A couple of the first cousins born with hypotonia and maternal polyhydramnios |
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| المؤلفون: | Mousa Ahmadpour‐kacho, Yadollah Zahed Pasha, Samira Pournajaf |
| المصدر: | Clinical Case Reports, Vol 12, Iss 2, Pp n/a-n/a (2024) |
| بيانات النشر: | Wiley, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Medicine (General) |
| مصطلحات موضوعية: | congenital, dystrophy, hypotonia, neonates, polyhydramnios, Medicine, Medicine (General), R5-920 |
| الوصف: | Key Clinical Message Congenital myotonic dystrophy should be considered in hypotonic infants with polyhydramniotic mothers with a positive history of myotonia. Abstract Congenital myotonic dystrophy (CDM) is a predominantly maternally inherited disease and results from increased numbers of cytosine, thymine, and guanine (CTG) repeats in the unstable DNA regions and presents as hypotonia in the neonatal period and myotonia in adulthood. This report aims to present two cases of CDM. A first‐cousin couple was born and hospitalized due to hypotonia at birth and a maternal history of polyhydramnios during this pregnancy. The first‐born baby girl was admitted to the NICU with tachypnea and hypotonia, clubfoot, and frog‐like posture. The pregnancy was complicated by polyhydramnios. Interestingly, her first cousin was born the next day with a similar picture and history. Myotonia was detected in their mothers. The concurrent presence of hypotonia and polyhydramnios as well as maternal myotonia in a first cousin should be considered CDM until proven otherwise and this was confirmed by the EMG‐ NCV test. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2050-0904 46909079 |
| Relation: | https://doaj.org/toc/2050-0904 |
| DOI: | 10.1002/ccr3.8503 |
| URL الوصول: | https://doaj.org/article/dabdeb28910f46909079f2da5c80958b |
| رقم الأكسشن: | edsdoj.bdeb28910f46909079f2da5c80958b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20500904 46909079 |
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| DOI: | 10.1002/ccr3.8503 |