دورية أكاديمية
Increase of Myocardial Ischemia Time and Short-Term Prognosis of Patients with Acute Myocardial Infarction during the First COVID-19 Pandemic Wave
العنوان: | Increase of Myocardial Ischemia Time and Short-Term Prognosis of Patients with Acute Myocardial Infarction during the First COVID-19 Pandemic Wave |
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المؤلفون: | Povilas Budrys, Mindaugas Lizaitis, Kamile Cerlinskaite-Bajore, Vilhelmas Bajoras, Greta Rodevic, Aurelija Martinonyte, Laurynas Dieckus, Ignas Badaras, Pranas Serpytis, Romualdas Gurevicius, Rasa Visinskiene, Romualdas Buivydas, Aleksandr Volodko, Egle Urbonaite, Jelena Celutkiene, Giedrius Davidavicius |
المصدر: | Medicina, Vol 57, Iss 12, p 1296 (2021) |
بيانات النشر: | MDPI AG, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Medicine (General) |
مصطلحات موضوعية: | COVID-19, myocardial infarction, ischemia time, percutaneous coronary intervention, Medicine (General), R5-920 |
الوصف: | Background and objectives: early reports showed a decrease in admission rates and an increase in mortality of patients with acute myocardial infarction (AMI) during the first wave of COVID-19 pandemic. We sought to investigate whether the COVID-19 pandemic and associated lockdown had an impact on the ischemia time and prognosis of patients suffering from AMI in the settings of low COVID-19 burden. Materials and Methods: we conducted a retrospective data analysis from a tertiary center in Lithuania of 818 patients with AMI. Data were collected from 1 March to 30 June in 2020 during the peri-lockdown period (2020 group; n = 278) and compared to the same period last year (2019 group; n = 326). The primary study endpoint was all-cause mortality during 3 months of follow-up. Secondary endpoints were heart failure severity (Killip class) on admission and ischemia time in patients with acute ST segment elevation myocardial infarction (STEMI). Results: there was a reduction of 14.7% in admission rate for acute myocardial infarction (AMI) during the peri-lockdown period. The 3-month mortality rate did not differ significantly (6.9% in 2020 vs. 10.5% in 2019, p = 0.341 for STEMI patients; 5.3% in 2020 vs. 2.6% in 2019, p = 0.374 for patients with acute myocardial infarction without ST segment elevation (NSTEMI)). More STEMI patients presented with Killip IV class in 2019 (13.5% vs. 5.5%, p = 0.043, respectively). There was an increase of door-to-PCI time (54.0 [42.0–86.0] in 2019; 63.5 [48.3–97.5] in 2020, p = 0.018) and first medical contact (FMC)-to-PCI time (101.0 [82.5–120.8] in 2019; 115 [97.0–154.5] in 2020, p = 0.01) during the pandemic period. Conclusions: There was a 14.7% reduction of admissions for AMI during the first wave of COVID-19. FMC-to-PCI time increased during the peri-lockdown period, however, it did not translate into worse survival during follow-up. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1648-9144 1010-660X |
Relation: | https://www.mdpi.com/1648-9144/57/12/1296; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144 |
DOI: | 10.3390/medicina57121296 |
URL الوصول: | https://doaj.org/article/be66ca17d8e6445da9691d8aaf358d92 |
رقم الأكسشن: | edsdoj.be66ca17d8e6445da9691d8aaf358d92 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 16489144 1010660X |
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DOI: | 10.3390/medicina57121296 |