دورية أكاديمية
Targeted Thrombolytic Enzymes Delivery
| العنوان: | Targeted Thrombolytic Enzymes Delivery |
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| المؤلفون: | Taimoor Hassan |
| المصدر: | Pakistan Journal of Medicine and Dentistry, Vol 11, Iss 2 (2024) |
| بيانات النشر: | ziauddin University, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Biochemistry LCC:Dentistry LCC:Therapeutics. Pharmacology LCC:Medicine (General) |
| مصطلحات موضوعية: | Biochemistry, QD415-436, Dentistry, RK1-715, Therapeutics. Pharmacology, RM1-950, Medicine (General), R5-920 |
| الوصف: | The intravascular delivery of thrombolytic medicines is required due to the small molecular sizes of the medications, resulting in systemic effects and the induction of the lytic state. Although the dose of tPA is higher than that encountered by a healthy organism, it is only partly provided (0.9 mg/kg for stroke, not more than 90 mg and100 mg for myocardial infarction) due to the rapid degradation of tPA upon delivery. Its blood lodging period is just a few minutes, as opposed to the newer type (Tenecteplase, TNKase®), which has a somewhat longer time to lodge blood. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2313-7371 2308-2593 |
| Relation: | https://ojs.zu.edu.pk/pjmd/article/view/1598; https://doaj.org/toc/2313-7371; https://doaj.org/toc/2308-2593 |
| DOI: | 10.36283/PJMD11-2/001 |
| URL الوصول: | https://doaj.org/article/cbef35f036a44f1d9c8a7783bbab1ee6 |
| رقم الأكسشن: | edsdoj.bef35f036a44f1d9c8a7783bbab1ee6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23137371 23082593 |
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| DOI: | 10.36283/PJMD11-2/001 |