دورية أكاديمية
A Case Report of Gemella sanguinis Isolated From Blood Cultures of a Patient With Mitral Valve Prolapse
العنوان: | A Case Report of Gemella sanguinis Isolated From Blood Cultures of a Patient With Mitral Valve Prolapse |
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المؤلفون: | Hyun Jin Kim, Sungmin Kym, Qute Choi |
المصدر: | Annals of Clinical Microbiology, Vol 25, Iss 4, Pp 163-168 (2022) |
بيانات النشر: | Korean Society of Clinical Microbiology, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Microbiology |
مصطلحات موضوعية: | gemella sanguinis, infectious endocarditis, maldi-tof ms, 16s rrna sequencing, Microbiology, QR1-502 |
الوصف: | Gemella sanguinis is a gram-positive, facultatively anaerobic coccus bacterium that has rarely been reported as a cause of infective endocarditis. A 41-year-old male patient with mitral valve prolapse visited the outpatient clinic presenting with fever. Transthoracic echocardiography and transesophageal echocardiography revealed myxomatous change and vegetation of the mitral valve. We isolated G. sanguinis from the patient’s blood, cultured it in both aerobic and anaerobic blood culture bottles, and identified it using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS; bioM.rieux, France) and 16s rRNA sequencing. The isolated G. sanguinis was highly susceptible to penicillin and vancomycin and intermediately susceptible to erythromycin, clindamycin, and levofloxacin. Following the American Heart Association recommendations, this highly penicillin-sensitive isolate was eradicated with ceftriaxone and gentamicin, and the patient recovered and was discharged. To the best of our knowledge, this is the first reported case in Korea where G. sanguinis, the causative agent of endocarditis, was identified using MALDI-TOF MS and 16s rRNA sequencing and was treated with only antibiotics and without surgical valve replacement. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English Korean |
تدمد: | 2288-0585 2288-6850 |
Relation: | https://www.acm.or.kr/acm_22-018/; https://doaj.org/toc/2288-0585; https://doaj.org/toc/2288-6850 |
DOI: | 10.5145/ACM.2022.25.4.6 |
URL الوصول: | https://doaj.org/article/bf8a571203404b5d804fc03de6386681 |
رقم الأكسشن: | edsdoj.bf8a571203404b5d804fc03de6386681 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22880585 22886850 |
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DOI: | 10.5145/ACM.2022.25.4.6 |