دورية أكاديمية

A Case Report of Gemella sanguinis Isolated From Blood Cultures of a Patient With Mitral Valve Prolapse

التفاصيل البيبلوغرافية
العنوان: A Case Report of Gemella sanguinis Isolated From Blood Cultures of a Patient With Mitral Valve Prolapse
المؤلفون: Hyun Jin Kim, Sungmin Kym, Qute Choi
المصدر: Annals of Clinical Microbiology, Vol 25, Iss 4, Pp 163-168 (2022)
بيانات النشر: Korean Society of Clinical Microbiology, 2022.
سنة النشر: 2022
المجموعة: LCC:Microbiology
مصطلحات موضوعية: gemella sanguinis, infectious endocarditis, maldi-tof ms, 16s rrna sequencing, Microbiology, QR1-502
الوصف: Gemella sanguinis is a gram-positive, facultatively anaerobic coccus bacterium that has rarely been reported as a cause of infective endocarditis. A 41-year-old male patient with mitral valve prolapse visited the outpatient clinic presenting with fever. Transthoracic echocardiography and transesophageal echocardiography revealed myxomatous change and vegetation of the mitral valve. We isolated G. sanguinis from the patient’s blood, cultured it in both aerobic and anaerobic blood culture bottles, and identified it using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS; bioM.rieux, France) and 16s rRNA sequencing. The isolated G. sanguinis was highly susceptible to penicillin and vancomycin and intermediately susceptible to erythromycin, clindamycin, and levofloxacin. Following the American Heart Association recommendations, this highly penicillin-sensitive isolate was eradicated with ceftriaxone and gentamicin, and the patient recovered and was discharged. To the best of our knowledge, this is the first reported case in Korea where G. sanguinis, the causative agent of endocarditis, was identified using MALDI-TOF MS and 16s rRNA sequencing and was treated with only antibiotics and without surgical valve replacement.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Korean
تدمد: 2288-0585
2288-6850
Relation: https://www.acm.or.kr/acm_22-018/; https://doaj.org/toc/2288-0585; https://doaj.org/toc/2288-6850
DOI: 10.5145/ACM.2022.25.4.6
URL الوصول: https://doaj.org/article/bf8a571203404b5d804fc03de6386681
رقم الأكسشن: edsdoj.bf8a571203404b5d804fc03de6386681
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22880585
22886850
DOI:10.5145/ACM.2022.25.4.6