دورية أكاديمية
In vivo hypoglycemic, antihyperglycemic and antidyslipidemic effects of the solvent fractions of Hagenia abyssinica leaves in mice
| العنوان: | In vivo hypoglycemic, antihyperglycemic and antidyslipidemic effects of the solvent fractions of Hagenia abyssinica leaves in mice |
|---|---|
| المؤلفون: | Zemene Demelash Kifle, Alem Endeshaw Woldeyohanin, Faisel Dula Sema, Simachew Gidey Debeb, Asmamaw Emagn Kasahun, Chilot Abiyu Demeke, Yaschilal Muche Belayneh |
| المصدر: | Metabolism Open, Vol 12, Iss , Pp 100139- (2021) |
| بيانات النشر: | Elsevier, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Physiology LCC:Biochemistry |
| مصطلحات موضوعية: | Antihyperglycemic, Hagenia abyssinica, Leaves, And streptozotocin, Physiology, QP1-981, Biochemistry, QD415-436 |
| الوصف: | Background: Hagenia abyssinica leaves have been used traditionally for the management of different diseases including diabetes mellitus (DM) although the antidiabetic effect of different solvent fractions of hydromethanol H. abyssinica leaf extract has not been scientifically studied. Thus, this study was conducted to investigate the in vivo hypoglycemic, antihyperglycemic and antidyslipidemic effects of the solvent fractions of Hagenia abyssinica leaf extract. Methods: The antidiabetic effect of the solvent fractions was evaluated in normal, oral glucose loaded and streptozotocin-induced diabetic mice. Hypoglycemic, antihyperglycemic, antidyslipidemic activities and effect on body weight change were evaluated after administration of three different doses of the solvent fractions (100, 200, and 400 mg/kg). One-way ANOVA followed by Tukey's post hoc test was used for data analysis, and p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2589-9368 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2589936821000633; https://doaj.org/toc/2589-9368 |
| DOI: | 10.1016/j.metop.2021.100139 |
| URL الوصول: | https://doaj.org/article/bfa041fad5ea4ca2b49b6029f6d62f10 |
| رقم الأكسشن: | edsdoj.bfa041fad5ea4ca2b49b6029f6d62f10 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 25899368 |
|---|---|
| DOI: | 10.1016/j.metop.2021.100139 |