دورية أكاديمية
Carcinogenic Risk from Lead and Cadmium Contaminating Cow Milk and Soya Beverage Brands Available in the Portuguese Market
| العنوان: | Carcinogenic Risk from Lead and Cadmium Contaminating Cow Milk and Soya Beverage Brands Available in the Portuguese Market |
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| المؤلفون: | Vanda Lopes de Andrade, Iolanda Ribeiro, Ana Paula Marreilha dos Santos, Michael Aschner, Maria Luisa Mateus |
| المصدر: | Journal of Xenobiotics, Vol 14, Iss 2, Pp 798-811 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Therapeutics. Pharmacology LCC:Toxicology. Poisons |
| مصطلحات موضوعية: | lead–cadmium mixture, cow milk, soya beverages, carcinogenic risk assessment, high consumers, children and adolescents, Therapeutics. Pharmacology, RM1-950, Toxicology. Poisons, RA1190-1270 |
| الوصف: | Our previous work demonstrated the presence of lead (Pb) and cadmium (Cd) contamination in cow milk (CM) and soy beverages (SBs) in Portugal. These metals share carcinogenic mechanisms, suggesting at least additive effects. Our goals were to assess carcinogenic risks from Pb and Cd intake detected in various CM and SB brands on the Portuguese market and to determine the relative contributions of Pb and Cd. Furthermore, we modeled different consumption scenarios for various age/body weight groups to estimate cumulative Excess Lifetime Carcinogenic Risk (ELCR). ELCR was computed by multiplying chronic daily intake by a cancer slope factor for each metal, with an ELCR > 1 × 10−4 indicating carcinogenic risk. Five CM and three SB brands posed cancer risks in children, with the highest values at 1.75 × 10−4 and 9.12 × 10−5, respectively; Pb had mean relative contributions of 87.8 ± 3.1% in CM and 54.9 ± 12.1% in SB. Carcinogenic risks were observed for children, adolescents, and adults in several CM or SB consumption scenarios, albeit at levels above typical Portuguese intakes. Strict monitoring of metal levels, such as Pb and Cd, is advised because CM is a component of many foods, including baby food. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2039-4713 2039-4705 |
| Relation: | https://www.mdpi.com/2039-4713/14/2/45; https://doaj.org/toc/2039-4705; https://doaj.org/toc/2039-4713 |
| DOI: | 10.3390/jox14020045 |
| URL الوصول: | https://doaj.org/article/cebfd11b47984500bf8ac86046394377 |
| رقم الأكسشن: | edsdoj.bfd11b47984500bf8ac86046394377 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20394713 20394705 |
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| DOI: | 10.3390/jox14020045 |