This cross-sectional study examined the relationship between childhood trauma, eating disorders, and sleep quality among registered hospital nurses in South Korea. Self-report questionnaires were answered by 279 nurses from six general hospitals. Factors affecting sleep quality were analyzed with a linear regression analysis. The factors that influenced sleep quality included age, alcohol consumption, chronic disease, BMI, and emotional abuse in childhood trauma. Hospital nurses need to increase their sleep health knowledge to maintain a healthy lifestyle while working as a nurse. Therefore, hospital and nursing managers should consider strategies to prevent and intervene in the sleep quality threats attributed to the adverse childhood experiences of hospital nurses.