دورية أكاديمية
IKKε isoform switching governs the immune response against EV71 infection
| العنوان: | IKKε isoform switching governs the immune response against EV71 infection |
|---|---|
| المؤلفون: | Ya-Ling Chang, Yu-Wen Liao, Min-Hsuan Chen, Sui-Yuan Chang, Yao-Ting Huang, Bing-Ching Ho, Sung-Liang Yu |
| المصدر: | Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021) |
| بيانات النشر: | Nature Portfolio, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Biology (General) |
| مصطلحات موضوعية: | Biology (General), QH301-705.5 |
| الوصف: | Chang et al. show that Enterovirus 71 (EV71) infection upregulates IKKε isoform 2 (IKKε v2), which in turn activates interferon regulatory factor 7 (IRF7). This study suggests that host cells trigger IKKε isoform switching to increase the production of interferon against EV71 infection, providing a potential strategy for boosting host’s antiviral defense. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2399-3642 10564527 |
| Relation: | https://doaj.org/toc/2399-3642 |
| DOI: | 10.1038/s42003-021-02187-x |
| URL الوصول: | https://doaj.org/article/cf0a06bd1056452785cc2fdda4a477a3 |
| رقم الأكسشن: | edsdoj.f0a06bd1056452785cc2fdda4a477a3 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 23993642 10564527 |
|---|---|
| DOI: | 10.1038/s42003-021-02187-x |