دورية أكاديمية
Pathological, histochemical, and immune-histochemical studies on some canine-skin neoplasm at Sharkia province, Egypt
العنوان: | Pathological, histochemical, and immune-histochemical studies on some canine-skin neoplasm at Sharkia province, Egypt |
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المؤلفون: | Hatem A. Zwai, Al-Sayed R. Al-Attar, Abdulla E. Morsi, Moustafa S. Abou-El-Fetouh |
المصدر: | Open Veterinary Journal, Vol 14, Iss (1) (Zagazig Veterinary Conference), Pp 481-499 (2024) |
بيانات النشر: | Tripoli University, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Zoology |
مصطلحات موضوعية: | dogs, skin tumors, trichoepithelioma, paraganglioma, melanoma, Zoology, QL1-991 |
الوصف: | Background: Cutaneous neoplastic disorders are often observed in small mammal pets, such as dogs, regardless of their gender. Aim: An important objective of this work was to give a full account of clinical, pathological, and immune-histochemical features of several skin tumours in dogs. Methods: This study was a case series in the hospital clinic, Faculty of Veterinary Medicine, Zagazig University, Egypt. Twenty-five dogs (14 males, and 11 females) were examined clinically during the period from March 2022 to October 2023. The skin swelling was collected from affected animals and then subjected to a detailed histopathological study to record the different gross and microscopic findings and confirmed the diagnosis by immunohistochemistry. Results: Skin neoplasia in dogs was exposed to various clinical signs, and the dogs' ages ranged between 3 to 11 years. Concerning tumor features, the majority of neoplasms were malignant (65.52%) more than benign (34.48%).The study revealed the presence of 29 cases of dogs showed neoplasia with different prevalence rate including squamous cell carcinoma (13.79%), mast cell tumor (6.89%), basal cell tumours (10.34%), histiocytoma (6.89%), trichoepithelioma (10.34%), transmissible venereal tumor (10.34%), trichilemmoma (3.44%), scalp paraganglioma (3.44%), pilomatricoma (10.34%), malignant melanomas (17.24%), and miscellaneous cases as fat necrosis (6.89%), in males and females dogs with different histopathological lesions and immunohistochemistry expressions for Pan-Cytokeratin (CK), melanocyte-differentiation antigens (S100 protein) and synaptophysin. Conclusion: Malignant melanomas (17.24%) are the extreme common cutaneous tumor diagnosed in this study. Meanwhile, benign tumors such as trichilemmoma, trichoepithelioma, pilomatricoma, and paraganglioma are less frequent in dogs. [Open Vet J 2024; 14(1.000): 481-499] |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2226-4485 2218-6050 |
Relation: | https://www.openveterinaryjournal.com/?mno=182392; https://doaj.org/toc/2226-4485; https://doaj.org/toc/2218-6050 |
DOI: | 10.5455/OVJ.2024.v14.i1.44 |
URL الوصول: | https://doaj.org/article/f1158563c0aa4cf3a9cbb405d2862c4b |
رقم الأكسشن: | edsdoj.f1158563c0aa4cf3a9cbb405d2862c4b |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22264485 22186050 |
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DOI: | 10.5455/OVJ.2024.v14.i1.44 |